9-Aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one (Seoul-Fluor) as a smart platform for colorful ratiometric fluorescent pH sensors

被引:34
作者
Kim, Eunha [1 ]
Lee, Sanghee [1 ]
Park, Seung Bum [1 ,2 ]
机构
[1] Seoul Natl Univ, Dept Chem, Seoul 151747, South Korea
[2] Seoul Natl Univ, Dept Biophys & Chem Biol, Seoul 151747, South Korea
基金
新加坡国家研究基金会;
关键词
INTRACELLULAR ZINC; CORE SKELETON; PROBES;
D O I
10.1039/c1cc12618k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this communication, we report that 9-aryl-1,2-dihydropyrrolo[3,4-b] indolizin-3-one (Seoul-Fluor) can serve as a potential platform for colorful ratiometric fluorescent pH sensors by simple incorporation of pH responsive elements on Seoul-Fluor. Seoul-Fluor-based fluorescent pH sensors allow the emission-and pH-tuning ability upon protonation by varying their pK(a) values and electronic characteristics of substituents by a rational design.
引用
收藏
页码:7734 / 7736
页数:3
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