Oral leiomyosarcomas: report of two cases with immunohistochemical profile

被引：14
作者：
Rodini, Camila Oliveira
Correa Pontes, Flavia Sirotheau
Rebelo Pontes, Helder Antonio
da Silva Santos, Paulo Sergio
Magalhaes, Marina Gallottini
Pinto, Decio Santos, Jr.
机构：
[1] Univ Sao Paulo, Sch Dent, Dept Stomatol Oral Pathol, BR-05508 Sao Paulo, Brazil
[2] Fed Univ Para, Sch Dent, Dept Pathol, BR-66059 Belem, Para, Brazil
[3] Barros Barreto Univ Hosp, Para, Brazil
来源：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 2007年 / 104卷 / 04期
关键词：
D O I：
10.1016/j.tripleo.2007.05.005
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Leiomyosarcoma of the oral cavity is a very rare tumor associated with aggressive clinical behavior and low survival. In this paper, we report 2 cases of leiomyosarcoma, affecting the gingival mucosa of a 54-year-old female and the maxillary bone of a 63-year-old male. Histologically, the tumors were composed of variably oriented fascicles of spindle-shaped cells with cigar-shaped nuclei and eosinophilic cytoplasm. The lesions were treated by surgical resection. Immunoreactivity to anti-vimentin, anti-smooth muscle actin, anti-desmin, anti-laminin, and anti-muscle-specific actin antibodies were found; conversely, the tumor cells were negative for anti-S100 and AE1/AE3 proteins. This report emphasizes the role of immunohistochemical study for correct diagnosis of leiomyosarcoma.
引用
收藏
页码：E50 / E55
页数：6
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