Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma

被引：21

作者：

Green, JA

Amaro, R

Barkin, JS

机构：

[1] Univ Miami, Mt Sinai Med Ctr, Sch Med, Div Gastroenterol, Miami Beach, FL 33140 USA

[2] Slocum Dickson Med Grp PC, New Hartford, NY USA

来源：

DIGESTIVE DISEASES AND SCIENCES | 2000年 / 45卷 / 12期

关键词：

gastroesophageal reflux; adenocarcinoma;

D O I：

10.1023/A:1005638924929

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A population-based, case-control study to investigate the possible association between gastroesophageal reflux (GER) and adenocarcinoma of the esophagus and gastric cardia was performed. It demonstrated an odds ratio of 7.7 for esophageal adenocarcinoma in patients with GER symptoms. The frequency, severity, and duration of symptoms correlated with an increased risk of esophageal adenocarcinoma. A weaker association was noted for GER and adenocarcinoma of the gastric cardia. No association surfaced between GER and squamous cell carcinoma of the esophagus.

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收藏

页码：2367 / 2368

页数：2

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