Synthesis of 3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one by Novel Palladium(II)-Catalyzed Cyclization and Ring-Closing Metathesis

被引：11

作者：

Chavan, Subhash P. ^{[1
]}

Pathak, Ashok B. ^{[1
]}

Pawar, Kailash P. ^{[1
]}

机构：

[1] Natl Chem Lab, CSIR, Div Organ Chem, Pune 411008, Maharashtra, India

来源：

SYNTHESIS-STUTTGART | 2015年 / 47卷 / 07期

关键词：

pyrrolinone; glimepiride; antidiabetic; metabolite; lactams; ring-closing metathesis; cyclization; RUTHENIUM CARBENE COMPLEXES; RCM; ISOMERIZATION; DERIVATIVES; PYRROLE; LIGANDS; ROUTE;

D O I：

10.1055/s-0034-1379985

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of 3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one is described starting from commercially available allylamine and 4-methoxybenzylamine employing palladium-catalyzed cyclization or ring-closing metathesis as the key steps.

引用

页码：955 / 960

页数：6

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