Synthesis of 3-Ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one by Novel Palladium(II)-Catalyzed Cyclization and Ring-Closing Metathesis

被引：11
|
作者：
Chavan, Subhash P. [1 ]
Pathak, Ashok B. [1 ]
Pawar, Kailash P. [1 ]
机构：
[1] Natl Chem Lab, CSIR, Div Organ Chem, Pune 411008, Maharashtra, India
来源：
SYNTHESIS-STUTTGART | 2015年 / 47卷 / 07期
关键词：
pyrrolinone; glimepiride; antidiabetic; metabolite; lactams; ring-closing metathesis; cyclization; RUTHENIUM CARBENE COMPLEXES; RCM; ISOMERIZATION; DERIVATIVES; PYRROLE; LIGANDS; ROUTE;
D O I：
10.1055/s-0034-1379985
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Synthesis of 3-ethyl-4-methyl-1,5-dihydro-2H-pyrrol-2-one is described starting from commercially available allylamine and 4-methoxybenzylamine employing palladium-catalyzed cyclization or ring-closing metathesis as the key steps.
引用
收藏
页码：955 / 960
页数：6
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