The effect of normovolemic hemodilution on c-Fos protein immunoreactivity in the postischemic rat brain cortex

被引：1
作者：
Miroslava, N [1 ]
Burda, J [1 ]
Danielisová, V [1 ]
Marsala, J [1 ]
机构：
[1] Slovak Acad Sci, Inst Neurobiol, Kosice 04001, Slovakia
来源：
INTERNATIONAL JOURNAL OF NEUROSCIENCE | 2005年 / 115卷 / 04期
关键词：
cerebral ischemia; c-Fos; hemodilution; neocortex; postischemic reperfusion; rats;
D O I：
10.1080/00207450590523422
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The hemodilution effect was evaluated in the parietal, temporal, and basal regions of postischemic rat brain neocortex by the immunohistochemical detection of the c-Fos protein. Rats were subjected to the four-vessel-occlusion and the hemodilution was used in one group of animals. Coronal sections of rat brains were used for immunohistochemical processing of c-Fos protein after different postischemic reperfusion intervals. The number of c-Fos positive neuronal nuclei was significantly decreased in the hemodilution group after 4 h of reperfusion in the parietal and basal neocortex compared to the reperfusion without hemodilution.
引用
收藏
页码：523 / 536
页数：14
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