Borane-catalyzed hydroboration of substituted alkenes by lithium borohydride or sodium borohydride

被引：6
|
作者：
Villiers, C [1 ]
Ephritikhine, M [1 ]
机构：
[1] CEA Saclay, CNRS, URA 331, DRECAM,DSM,Serv Chim Mol, F-91191 Gif Sur Yvette, France
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 44期
关键词：
hydroboration; alkenes; borohydride; catalysis;
D O I：
10.1016/j.tetlet.2003.09.055
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In the presence of a catalytic amount of (BH3Me2S)-Me-., TiCl4 or Me3SiCl, LiBH4 or NaBH4 are capable of hydroborating alkenes by following the unusual order of decreasing reactivity: tetramethylethylene > 1-methylcyclohexene > cyclohexene; the key step of the catalytic cycle is the exchange reaction between LiBH4 and the mono- or dialkylboranes resulting from hydroboration of the more substituted alkenes with BH3. (C) 2003 Elsevier Ltd. All rights reserved.
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页码：8077 / 8079
页数：3
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