Galaxy: A platform for interactive large-scale genome analysis

被引：1474

作者：

Giardine, B

Riemer, C

Hardison, RC

Burhans, R

Elnitski, L

Shah, P

Zhang, Y

Blankenberg, D

Albert, I

Taylor, J

Miller, W

Kent, WJ

Nekrutenko, A ^{[1
]}

机构：

[1] Penn State Univ, Huck Inst Life Sci, Ctr Comparat Genom & Bioinformat, University Pk, PA 16802 USA

[2] NHGRI, Bethesda, MD 20892 USA

[3] Univ Calif Santa Cruz, Dept Comp Sci & Engn, Santa Cruz, CA 95064 USA

来源：

GENOME RESEARCH | 2005年 / 15卷 / 10期

关键词：

D O I：

10.1101/gr.4086505

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Accessing and analyzing the exponentially expanding genomic sequence and functional data pose a challenge for biomedical researchers. Here we describe ail interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and Visualize the results. The heart of Galaxy is a flexible history system that stores the queries from each user; performs operations Such as intersections, unions, and Subtractions; and links to other computational tools. Galaxy call be accessed at http://g2.bx.psu.edu.

引用

页码：1451 / 1455

页数：5

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