Optimized serodiagnosis of Mycoplasma pneumoniae infections

被引：25

作者：

Dumke, Roger ^{[1
]}

Strubel, Andreas ^{[2
]}

Cyncynatus, Camille ^{[3
]}

Nuyttens, Helene ^{[3
]}

Herrmann, Richard ^{[4
]}

Lueck, Christian ^{[1
]}

Jacobs, Enno ^{[1
]}

机构：

[1] Tech Univ Dresden, Inst Med Microbiol & Hyg, D-01307 Dresden, Germany

[2] Sekisui Virotech GmbH, D-65428 Russelsheim, Germany

[3] Gen BioSci, F-91380 Chilly Mazarin, France

[4] Heidelberg Univ, ZMBH, D-69120 Heidelberg, Germany

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2012年 / 73卷 / 02期

关键词：

Mycoplasma pneumoniae; Immunoblot; Community-acquired pneumonia; Recombinant proteins; COMMERCIAL TESTS; P1; ADHESIN; PROTEIN; IDENTIFICATION; ANTIBODIES; DIAGNOSIS; EXPRESSION; P200; PCR;

D O I：

10.1016/j.diagmicrobio.2012.02.014

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive patients were confirmed by our immunoblotting approach having a specificity between 92.6% and 100%. (C) 2012 Elsevier Inc. All rights reserved.

引用

页码：200 / 203

页数：4

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