Optimized serodiagnosis of Mycoplasma pneumoniae infections

被引：25
作者：
Dumke, Roger [1 ]
Strubel, Andreas [2 ]
Cyncynatus, Camille [3 ]
Nuyttens, Helene [3 ]
Herrmann, Richard [4 ]
Lueck, Christian [1 ]
Jacobs, Enno [1 ]
机构：
[1] Tech Univ Dresden, Inst Med Microbiol & Hyg, D-01307 Dresden, Germany
[2] Sekisui Virotech GmbH, D-65428 Russelsheim, Germany
[3] Gen BioSci, F-91380 Chilly Mazarin, France
[4] Heidelberg Univ, ZMBH, D-69120 Heidelberg, Germany
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2012年 / 73卷 / 02期
关键词：
Mycoplasma pneumoniae; Immunoblot; Community-acquired pneumonia; Recombinant proteins; COMMERCIAL TESTS; P1; ADHESIN; PROTEIN; IDENTIFICATION; ANTIBODIES; DIAGNOSIS; EXPRESSION; P200; PCR;
D O I：
10.1016/j.diagmicrobio.2012.02.014
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Serologic methods are well established for the diagnosis of Mycoplasma pneumoniae infections in humans, but they are less sensitive than polymerase chain reaction (PCR). To improve their sensitivity, a new panel of antigens was tested. Compared with PCR results, up to 92% of PCR-positive patients were confirmed by our immunoblotting approach having a specificity between 92.6% and 100%. (C) 2012 Elsevier Inc. All rights reserved.
引用
收藏
页码：200 / 203
页数：4
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