Intravenous immunoglobulin and anti-D in idiopathic thrombocytopenic purpura (ITP): Mechanisms of action

被引：35

作者：

Lazarus, AH ^{[1
]}

Freedman, J ^{[1
]}

Semple, JW ^{[1
]}

机构：

[1] Canadian Blood Serv, Toronto Ctr, Toronto, ON, Canada

来源：

TRANSFUSION SCIENCE | 1998年 / 19卷 / 03期

关键词：

D O I：

10.1016/S0955-3886(98)00043-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infusion of large amounts of intravenous immunoglobulin (MG) or anti-D can reverse the low platelet count in patients with ITP within hours of the initiation of treatment. In some cases, the effects of IVIG appear to far outlast several half-lives of the product. Several mechanisms have been proposed to explain these rapid and long term effects and these will be discussed in this review. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：289 / 294

页数：6

共 34 条

[1]

ANDERSSON JP, 1990, IMMUNOLOGY, V71, P372

[2]

ANDERSSON UG, 1993, IMMUNOLOGY, V79, P211

[3]

ATLAS E, 1993, BLOOD, V81, P538

[4]

AUKRUST P, 1994, BLOOD, V84, P2136

[5]

BASTA M, 1989, BLOOD, V74, P326

[6]

BERCHTOLD P, 1989, BLOOD, V74, P2414

[7] AUTOIMMUNE THROMBOCYTOPENIA - ANTI-GLYCOPROTEIN IIB/IIIA AUTO ANTIBODIES ARE REDUCED AFTER HUMAN ANTI-D IMMUNOGLOBULIN TREATMENT [J].

BOUGHTON, BJ ;

COOKE, RMS ;

SMITH, NA ;

SIMPSON, AW .

AUTOIMMUNITY, 1994, 18 (02) :141-144

[8] TREATMENT OF ACUTE IDIOPATHIC THROMBOCYTOPENIC PURPURA OF CHILDHOOD WITH INTRAVENOUS IMMUNOGLOBULIN-G - COMPARATIVE EFFICACY OF 7S AND 5S PREPARATIONS [J].

BURDACH, SEG ;

EVERS, KG ;

GEURSEN, RG .

JOURNAL OF PEDIATRICS, 1986, 109 (05) :770-775

[9]

BUSSEL JB, 1983, BLOOD, V62, P480

[10]

BUSSEL JB, 1991, BLOOD, V77, P1884

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