Carbapenem-resistant Pseudomonas aeruginosa - clonal spread in Southern Brazil and in the State of Goias

被引：13

作者：

Scheffer, Mara Cristina ^{[2
]}

Gales, Ana Cristina ^{[3
]}

Barth, Afonso Luis ^{[4
]}

do Carmo Filho, Jose Rodrigues ^{[5
,6
]}

Dalla-Costa, Libera Maria ^{[1
]}

机构：

[1] Univ Fed Parana, Hosp Clin, Serv Anal Clin, BR-80060000 Curitiba, Parana, Brazil

[2] Univ Fed Santa Catarina, Univ Hosp, Serv Patol Clin, BR-88040900 Florianopolis, SC, Brazil

[3] Univ Fed Sao Paulo, Dept Doencas Infecciosas, Sao Paulo, Brazil

[4] Hosp Clin Porto Alegre, Serv Patol Clin, Porto Alegre, RS, Brazil

[5] Univ Catolica Goias, Dept Enfermagem, Goiania, Go, Brazil

[6] Univ Catolica Goias, Dept Med, Goiania, Go, Brazil

来源：

BRAZILIAN JOURNAL OF INFECTIOUS DISEASES | 2010年 / 14卷 / 05期

关键词：

P; aeruginosa; carbapenem resistance; metallo-beta-lactamase; METALLO-BETA-LACTAMASE; SPM-1;

D O I：

10.1590/S1413-86702010000500014

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This study evaluated the clonal spread of carbapenem-resistant P. aeruginosa producing SPM-1 type metallo-beta-lactamase (MBL), at the university hospital of Florianopolis, Santa Catarina, Brazil, compared to an epidemic clone previously reported, as well as strains collected in other three Brazilian states. Among the isolates, 17 (62%) were clonal and highly related to strains from other regions of Brazil. Six clonal strains harbored the bla(SPM-1) gene. The finding of a unique SPM-1 producer clone suggests that its dissemination has contributed to the high resistance to carbapenems in Brazilian hospitals.

引用

页码：508 / 509

页数：2

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