Breast magnetic resonance imaging for preoperative locoregional staging

被引:92
作者
Hollingsworth, Alan B. [1 ]
Stough, Rebecca G. [2 ]
O'Dell, Carol A. [2 ]
Brekke, Charles E. [2 ]
机构
[1] Mercy Hlth Ctr, Dept Surg, Oklahoma City, OK USA
[2] Mercy Womens Ctr, Mercy Hlth Ctr, Dept Radiol, Oklahoma City, OK USA
关键词
breast cancer; breast MRI; preoperative staging; multicentricity; contralateral; breast conservation; therapeutic options;
D O I
10.1016/j.amjsurg.2007.10.009
中图分类号
R61 [外科手术学];
学科分类号
摘要
BACKGROUND: Breast magnetic resonance imaging (MRI) has been recommended increasingly in the preoperative setting for patients newly diagnosed with malignancy to evaluate tumor extent, multicentricity, and contralateral disease. METHODS: Results of conventional imaging, breast MRI, and pathology were analyzed from 603 consecutive breast cancer patients who underwent MRI preoperatively. The focus of this retrospective study was imaging-histologic correlation. RESULTS: Reoperation for positive margins after lumpectomy occurred in 8.8% of patients. Multicentricity was identified by MRI alone in 7.7% of patients, whereas 3.7% were found to have contralateral cancer by MRI. The sensitivity of MRI was 93% in detecting multicentric disease and 88% for contralateral disease, whereas sensitivity for conventional imaging was 46% and 19%, respectively. Unsuspected disease was identified by MRI equally for invasive ductal and ductal carcinoma in situ histology, whereas multicentricity was found more frequently with invasive lobular carcinoma. CONCLUSIONS: Breast MRI is recommended for preoperative evaluation of the newly diagnosed breast cancer patient. (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:389 / 397
页数:9
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