A benzoboroxole-functionalized monolithic column for the selective enrichment and separation of cis-diol containing biomolecules

被引:145
作者
Li, Hengye [1 ]
Wang, Heye [1 ]
Liu, Yunchun [1 ]
Liu, Zhen [1 ]
机构
[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Analyt Chem Life Sci, Nanjing 210093, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
BORONATE; BINDING; ACID; GLYCOPEPTIDES; RECEPTOR; CAPTURE; CHROMATOGRAPHY; NANOPARTICLES; POLYMERS;
D O I
10.1039/c2cc30230f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A benzoboroxole-functionalized monolithic column was synthesized, which exhibited the best specificity and affinity towards cis-diol containing biomolecules as compared with the boronate affinity monolithic columns reported as well as significant secondary separation capability under acidic conditions.
引用
收藏
页码:4115 / 4117
页数:3
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共 30 条
  • [1] Benzoboroxoles as efficient glycopyranoside-binding agents in physiological conditions:: Structure and selectivity of complex formation
    Berube, Marie
    Dowlut, Meenakshi
    Hall, Dennis G.
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2008, 73 (17) : 6471 - 6479
  • [2] Boronate affinity monolith for highly selective enrichment of glycopeptides and glycoproteins
    Chen, Ming
    Lu, Yang
    Ma, Qiao
    Guo, Lin
    Feng, Yu-Qi
    [J]. ANALYST, 2009, 134 (10) : 2158 - 2164
  • [3] Synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease
    Ding, Charles Z.
    Zhang, Yong-Kang
    Li, Xianfeng
    Liu, Yang
    Zhang, Suoming
    Zhou, Yasheen
    Plattner, Jacob J.
    Baker, Stephen J.
    Liu, Liang
    Duan, Maosheng
    Jarvest, Richard L.
    Ji, Jingjing
    Kazmierski, Wieslaw M.
    Tallant, Matthew D.
    Wright, Lois L.
    Smith, Gary K.
    Crosby, Renae M.
    Wang, Amy A.
    Ni, Zhi-Jie
    Zou, Wuxin
    Wright, Jon
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (24) : 7317 - 7322
  • [4] An improved class of sugar-binding boronic acids, soluble and capable of complexing glycosides in neutral water
    Dowlut, M
    Hall, DG
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (13) : 4226 - 4227
  • [5] CONTINUOUS BEDS - HIGH-RESOLVING, COST-EFFECTIVE CHROMATOGRAPHIC MATRICES
    HJERTEN, S
    LI, YM
    LIAO, JL
    MOHAMMAD, J
    NAKAZATO, K
    PETTERSSON, G
    [J]. NATURE, 1992, 356 (6372) : 810 - 811
  • [6] Saccharide sensing with molecular receptors based on boronic acid
    James, TD
    Sandanayake, KRAS
    Shinkai, S
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1996, 35 (17) : 1910 - 1922
  • [7] Multivalent Benzoboroxole Functionalized Polymers as gp120 Glycan Targeted Microbicide Entry Inhibitors
    Jay, Julie I.
    Lai, Bonnie E.
    Myszka, David G.
    Mahalingam, Alamelu
    Langheinrich, Kris
    Katz, David F.
    Kiser, Patrick F.
    [J]. MOLECULAR PHARMACEUTICS, 2010, 7 (01) : 116 - 129
  • [8] A Fast Capillary Electrophoresis Method for Separation and Quantification of Modified Nucleosides in Urinary Samples
    Jiang, Yongqing
    Ma, Yinfa
    [J]. ANALYTICAL CHEMISTRY, 2009, 81 (15) : 6474 - 6480
  • [9] Chromatographic characterization of hydrophilic interaction liquid chromatography stationary phases: Hydrophilicity, charge effects, structural selectivity, and separation efficiency
    Kawachi, Yuusuke
    Ikegami, Tohru
    Takubo, Hirotaka
    Ikegami, Yuka
    Miyamoto, Masatoshi
    Tanaka, Nobuo
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (35) : 5903 - 5919
  • [10] Immobilization of aminophenylboronic acid on magnetic beads for the direct determination of glycoproteins by matrix assisted laser desorption ionization mass spectrometry
    Lee, JH
    Kim, YS
    Ha, MY
    Lee, EK
    Choo, JB
    [J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2005, 16 (09) : 1456 - 1460