Effects of a home-based exercise intervention on fatigue in postpartum depressed women:: Results of a randomized controlled trial

Background Fatigue is prevalent during the postpartum period and may be heightened in postpartum depressed women. Purpose To evaluate the efficacy of a home-based exercise intervention in reducing physical and mental fatigue scores in postpartum depressed women. Methods Eighty-eight women in the postpartum (4-38 weeks) obtaining a score >= 10 on the Edinburgh Postnatal Depression Scale (EPDS) were randomly assigned to a 12-week individualized home-based intervention (n=46) or a control group (n=42). All participants completed a cardiovascular fitness test at baseline. Outcomes were physical and mental fatigue scores and were measured at baseline, posttreatment and 3 months posttreatment. Results On the basis of intent-to-treat analyses, compared to the control group, women in the exercise group showed significantly greater reduction in physical fatigue at posttreatment [mean change= -4.07, (95% CI, (-5.15, -2.98)] and 3 months posttreatment [mean change=-4.24, (95% CI, (-5.36, -3.12)]. Significant reductions in mental fatigue with exercise were observed at posttreatment for women reporting lower physical fatigue at baseline. Conclusions Fatigue is a common symptom experienced in the postpartum that can be heightened by depression. The findings show that home-based exercise can reduce physical and mental fatigue in postpartum depressed women.