Value of pre-intervention CT perfusion imaging in acute ischemic stroke prognosis

被引：22

作者：

Katyal, Anubhav ^{[1
,4
]}

Bhaskar, Sonu Menachem Maimonides ^{[1
,2
,3
,4
,5
,6
,7
,8
]}

机构：

[1] Ingham Inst Appl Med Res, Clin Sci Stream, Neurovasc Imaging Lab, Sydney, NSW, Australia

[2] Liverpool Hosp, Dept Neurol & Neurophysiol, Sydney, NSW, Australia

[3] South West Sydney Local Hlth Dist SWSLHD, Sydney, NSW, Australia

[4] Univ New South Wales UNSW, South Western Sydney Clin Sch, Sydney, NSW, Australia

[5] Ingham Inst Appl Med Res, Stroke & Neurol Res Grp, Sydney, NSW, Australia

[6] NSW Hlth Statewide Biobank, NSW Brain Clot Bank, Sydney, NSW, Australia

[7] NSW Hlth Pathol, Sydney, NSW, Australia

[8] Thrombolysis & Endovasc WorkFLOw Network TEFLON, Sydney, NSW, Australia

来源：

DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY | 2021年 / 27卷 / 06期

关键词：

COMPUTED-TOMOGRAPHY PERFUSION; BRAIN-BARRIER PERMEABILITY; HEALTH-CARE PROFESSIONALS; HEMORRHAGIC TRANSFORMATION; BLOOD-VOLUME; COLLATERAL CIRCULATION; ENDOVASCULAR TREATMENT; CEREBRAL INFARCTION; DIFFUSION MISMATCH; HYPERACUTE STROKE;

D O I：

10.5152/dir.2021.20805

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Noninvasive imaging plays an important tole in acute stroke towards diagnosis and ongoing management of patients. Systemic thrombolysis and endovascular thrombectomy (EVT) are pioven treatments currently used in standards of care in acute stroke settings. The role of computed tomography angiography (CTA) in selecting patients with large vessel occlusion for EVT is well established. However, the value of CT perfusion (CTP) imaging in predicting outcomes after spoke remains ambiguous. This article critically evaluates the value of multimodal CT imaging in early diagnosis and prognosis of acute ischemic stroke with a focus on the iole of CTP in delineating tissue characteristics, patient selection, and outcomes after reperfusion therapy. Insights on various technical and clinical considerations relevant to CTP applications in acute ischemic stroke, recommendations for existing workflow, and future areas of research are discussed.

引用

页码：774 / 785

页数：12

共 86 条

[1] Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging [J].

Albers, G. W. ;

Marks, M. P. ;

Kemp, S. ;

Christensen, S. ;

Tsai, J. P. ;

Ortega-Gutierrez, S. ;

McTaggart, R. A. ;

Torbey, M. T. ;

Kim-Tenser, M. ;

Leslie-Mazwi, T. ;

Sarraj, A. ;

Kasner, S. E. ;

Ansari, S. A. ;

Yeatts, S. D. ;

Hamilton, S. ;

Mlynash, M. ;

Heit, J. J. ;

Zaharchuk, G. ;

Kim, S. ;

Carrozzella, J. ;

Palesch, Y. Y. ;

Demchuk, A. M. ;

Bammer, R. ;

Lavori, P. W. ;

Broderick, J. P. ;

Lansberg, M. G. .

NEW ENGLAND JOURNAL OF MEDICINE, 2018, 378 (08) :708-718

[2] Predictors of hemorrhagic transformation occurring spontaneously and on anticoagulants in patients with acute ischemic stroke [J].

Alexandrov, AV ;

Black, SE ;

Ehrlich, LE ;

Caldwell, CB ;

Norris, JW .

STROKE, 1997, 28 (06) :1198-1202

[3]

Arenillas JF, 2018, J CEREBR BLOOD F MET, V38, P1839, DOI 10.1177/0271678X17740293

[4] Alberta stroke program early CT scoring of CT perfusion in early stroke visualization and assessment [J].

Aviv, R. I. ;

Mandelcorn, J. ;

Chakraborty, S. ;

Gladstone, D. ;

Malham, S. ;

Tomlinson, G. ;

Fox, A. J. ;

Symons, S. .

AMERICAN JOURNAL OF NEURORADIOLOGY, 2007, 28 (10) :1975-1980

[5] Early stroke detection and extent: impact of experience and the role of computed tomography angiography source images [J].

Aviv, R. I. ;

Shelef, I. ;

Malam, S. ;

Chakraborty, S. ;

Sahas, D. J. ;

Tomlinson, G. ;

Symons, S. ;

Fox, A. J. .

CLINICAL RADIOLOGY, 2007, 62 (05) :447-452

[6] Hemorrhagic Transformation of Ischemic Stroke: Prediction with CT Perfusion [J].

Aviv, Richard I. ;

d'Esterre, Christopher D. ;

Murphy, Blake D. ;

Hopyan, Julia J. ;

Buck, Brian ;

Mallia, Gabriella ;

Li, Vivian ;

Zhang, Liying ;

Symons, Sean P. ;

Lee, Ting-Yim .

RADIOLOGY, 2009, 250 (03) :867-877

[7] Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy [J].

Barber, PA ;

Demchuk, AM ;

Zhang, JJ ;

Buchan, AM .

LANCET, 2000, 355 (9216) :1670-1674

[8] Ischemic core thresholds change with time to reperfusion: A case control study [J].

Bivard, Andrew ;

Kleinig, Tim ;

Miteff, Ferdinand ;

Butcher, Kenneth ;

Lin, Longting ;

Levi, Christopher ;

Parsons, Mark .

ANNALS OF NEUROLOGY, 2017, 82 (06) :995-1003

[9] Perfusion computed tomography to assist decision making for stroke thrombolysis [J].

Bivard, Andrew ;

Levi, Christopher ;

Krishnamurthy, Venkatesh ;

McElduff, Patrick ;

Miteff, Ferdi ;

Spratt, Neil J. ;

Bateman, Grant ;

Donnan, Geoffrey ;

Davis, Stephen ;

Parsons, Mark .

BRAIN, 2015, 138 :1919-1931

[10] Perfusion CT in Acute Stroke: A Comprehensive Analysis of Infarct and Penumbra [J].

Bivard, Andrew ;

Levi, Christopher ;

Spratt, Neil ;

Parsons, Mark .

RADIOLOGY, 2013, 267 (02) :543-550

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