Hemorrhagic manifestation of megaloblastic anemia: report of two cases and literature review

被引:4
作者
Masoodi, Ibrahim [1 ]
Kakar, Atul [2 ]
Byotra, Shrishti P. [2 ]
Sachdev, Munish K. [2 ]
Hussain, Shabnum [2 ]
机构
[1] King Fahad Med City, Dept Gastroenterol, Riyadh, Saudi Arabia
[2] Sir Ganga Ram Hosp, Dept Med, New Delhi, India
关键词
hemetemesis; megaloblastic anemia; melena; platelet dysfunction; thrombocytopenia;
D O I
10.1097/MBC.0b013e328343f8eb
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Megaloblastic anemia is not uncommon in developing countries. Its presentation as thrombocytopenia and hemorrhagic manifestation are, however, rare. We describe the clinical scenario in two young patients who presented to the emergency room of Sir Ganga Ram Hospital, a tertiary care center in New Delhi, India, with pancytopenia and bleeding diathesis. Both patients improved after B12 supplementation. Reports of two cases and a brief review is presented. Blood Coagul Fibrinolysis 22:234-235 (c) 2011 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
引用
收藏
页码:234 / 235
页数:2
相关论文
共 9 条
[1]  
Chandra Jagdish, 2002, Indian Pediatr, V39, P453
[2]  
Ghosh K, 1991, Platelets, V2, P153, DOI 10.3109/09537109109006026
[3]  
Gomber S, 1998, Indian Pediatr, V35, P55
[4]   PLATELET DYSFUNCTION IN PATIENTS WITH VITAMIN-B12 DEFICIENCY [J].
INGEBERG, S ;
STOFFERSEN, E .
ACTA HAEMATOLOGICA, 1979, 61 (02) :75-79
[5]  
Jaswal T S, 2000, Indian J Pathol Microbiol, V43, P325
[6]  
MARWAHA R K, 1989, Indian Journal of Pediatrics, V56, P243, DOI 10.1007/BF02726618
[7]  
SARODE R, 1989, TROP GEOGR MED, V41, P331
[8]   HAEMORRHAGE ASSOCIATED WITH THROMBOCYTOPENIA IN MEGALOBLASTIC ANAEMIA [J].
SMITH, MD ;
SMITH, DA ;
FLETCHER, M .
BMJ-BRITISH MEDICAL JOURNAL, 1962, (5283) :982-+
[9]   Vitamin B21 eficiency as a worldwide problem [J].
Stabler, SP ;
Allen, RH .
ANNUAL REVIEW OF NUTRITION, 2004, 24 :299-326