Biology of aging: theories, mechanisms, and perspectives

被引：11
作者：
D'Aquino Oliveira Teixeira, Ilka Niceia [1 ]
Guariento, Maria Elena [2 ]
机构：
[1] Univ Fed Parana, BR-80011970 Curitiba, Parana, Brazil
[2] Univ Estadual Campinas, BR-13081970 Campinas, SP, Brazil
来源：
CIENCIA & SAUDE COLETIVA | 2010年 / 15卷 / 06期
关键词：
Biology; Aging; Cell aging; Cell death; Aged; CELL-DEATH; WERNER SYNDROME; AGE; MITOCHONDRIA; EXPRESSION; APOPTOSIS; TURNOVER; CULTURE; STRESS;
D O I：
10.1590/S1413-81232010000600022
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The article reviews the major biological theories of aging, and discusses the most relevant mechanisms to explain the aging process. It begins with the evolutionary theories, explores the molecular-cellular mechanisms, and presents the perspective of the systemic theories. The complex etiology of aging is a challenge to the researchers. The knowledge on that phenomenon develops towards an integrative approach.
引用
收藏
页码：2845 / 2857
页数：13
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