Increased levels of oxidants and reduced antioxidants in semen of infertile men with varicocele

被引:75
作者
Abd-Elmoaty, Mohamed Ahmed [2 ]
Saleh, Ramadan [3 ]
Sharma, Rakesh [1 ]
Agarwal, Ashok [1 ]
机构
[1] Cleveland Clin, Ctr Reprod Med, Glickman Urol & Kidney Inst, Cleveland, OH 44195 USA
[2] Sohag Univ, Dept Med Biochem, Fac Med, Sohag, Egypt
[3] Sohag Univ, Dept Dermatol Venereol & Androl, Fac Med, Sohag, Egypt
关键词
OXYGEN SPECIES LEVELS; INCREASED NITRIC-OXIDE; OXIDATIVE STRESS; HUMAN SPERMATOZOA; SPERM MOTILITY; SEMINAL PLASMA; PEROXYNITRITE; FERTILE; VEIN; DYSFUNCTION;
D O I
10.1016/j.fertnstert.2009.12.039
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Significantly higher levels of oxidants (malonaldehyde and nitric oxide) and reduced levels of antioxidants (superoxide dismutase, glutathione peroxidase, catalase, and ascorbic acid) are seen in semen of infertile men with varicocele. Seminal oxidative stress (OS) seen in men with varicocele is associated with sperm motility and grade of varicocele. Copyright © 2010 American Society for Reproductive Medicine, Published by Elsevier Inc.
引用
收藏
页码:1531 / 1534
页数:4
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