Bioaerosol analysis by single particle mass spectrometry

被引:21
|
作者
Kleefsman, Ineke
Stowers, Michael A.
Verheijen, Peter J. T.
Van Wuijckhuijse, Arjan L.
Kientz, Charles E.
Marijnissen, Jan C. M.
机构
[1] Delft Univ Technol, NL-2628 BL Delft, Netherlands
[2] TNO, Prins Maurits Lab, NL-2288 GJ Rijswijk, Netherlands
关键词
aerosol MALDI mass spectrometry; bioaerosols; fluorescence; on-line analysis;
D O I
10.1002/ppsc.200601049
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
The performance and improvements of an aerosol mass spectrometer for the real time analysis of bioaerosol particles is described. The instrument can preselect the biological aerosol particles from non-biological particles, by recording the emitted fluorescence when the particles are irradiated with 266 nm laser light. ne fluorescing particles are further investigated by mass spectrometry. With the current performance of the mass spectrometer the produced mass spectra have high resolution and cover a mass range up to 85 kDalton. The capability of the aerosol mass spectrometer to produce good quality spectra of bacteria particles is shown with a mass spectrum of Erwinia herbicola. For the application of the aerosol mass spectrometer the possible interference of (background) soot particles onto the preselection is investigated and a minor interference is determined.
引用
收藏
页码:85 / 90
页数:6
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