Usefulness and clinical relevance of left ventricular global longitudinal systolic strain in patients with heart failure with preserved ejection fraction

被引:18
作者
Tschoepe, Carsten [1 ,2 ,3 ,4 ]
Senni, Michele [5 ]
机构
[1] Charite Univ Med Berlin, Dept Internal Med & Cardiol, Campus Virchow Klinikum Augustenburgerplatz 1, DE-13353 Berlin, Germany
[2] German Ctr Cardiovasc Res DZHK, Berlin, Germany
[3] Berlin Inst Hlth BIH, Berlin, Germany
[4] Berlin Ctr Regenerat Therapies BCRT, Campus Virchow Klinikum CVK, Berlin, Germany
[5] Papa Giovanni XXIII Hosp, Cardiovasc Dept, Cardiol Div, Bergamo, Italy
关键词
Global longitudinal strain; Heart failure; Echocardiography; SPECKLE-TRACKING ECHOCARDIOGRAPHY; DIASTOLIC FUNCTION; MECHANICAL DYSSYNCHRONY; EXERCISE INTOLERANCE; MYOCARDIAL FIBROSIS; ACTIVE RELAXATION; FILLING PRESSURES; DYSFUNCTION; DIAGNOSIS; ABNORMALITIES;
D O I
10.1007/s10741-019-09853-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In recent years, several studies have shown the usefulness and clinical relevance of left ventricular global longitudinal systolic strain (GLS) in different cardiovascular diseases. In line with this, the role of GLS in patients with heart failure with preserved ejection fraction (HFpEF) has achieved great importance in this predominant form of heart failure in the last years. In this regard, GLS has shown to be not only a sensitive parameter to detect subtle myocardial abnormalities but also a parameter of clinical and prognostic relevance in patients with HFpEF. In this review, we analyze the current evidence concerning the clinical relevance of GLS in patients with HFpEF and we discuss the potential usefulness of GLS in this complex and heterogeneous condition for which so far no effective therapy exists.
引用
收藏
页码:67 / 73
页数:7
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