Synthesis of some nucleosides derivatives from L-rhamnose with expected biological activity

被引：8
作者：
Ghoneim, Amira Atef [1 ]
机构：
[1] Zagazig Univ, Fac Sci, Dept Chem, Zagazig, Egypt
来源：
CHEMISTRY CENTRAL JOURNAL | 2011年 / 5卷
关键词：
MYCOBACTERIUM-TUBERCULOSIS; MASS-SPECTROMETRY; ARABINOGALACTAN; CIPROFLOXACIN; FRAGMENTS; ESTERS;
D O I：
10.1186/1752-153X-5-7
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect beta-L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of (3S, 4S, 5S, 6R) 3, 4, 5-triacetoxy-2-methyl-7,9-diaza-1-oxa-spiro [4,5]decane-10-one-8-thione (7).
引用
收藏
页数：7
相关论文
共 19 条
[1]   Novel synthesis of thieno[2,3-b]pyridine and substituted 2-thienylthiourea derivatives as antibiotic agents [J].
Al-Omran, F ;
El-Khair, AA .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2004, 41 (06) :909-914
[2]   Synthesis and biological effects of new derivatives of benzotriazole as antimicrobial and antifungal agents [J].
Al-Omran, F ;
Mohareb, RM ;
El-Khair, AA .
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2002, 39 (05) :877-883
[3]   A NEW INTERPRETATION OF THE STRUCTURE OF THE MYCOLYL ARABINOGALACTAN COMPLEX OF MYCOBACTERIUM-TUBERCULOSIS AS REVEALED THROUGH CHARACTERIZATION OF OLIGOGLYCOSYLALDITOL FRAGMENTS BY FAST-ATOM-BOMBARDMENT MASS-SPECTROMETRY AND H-1 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY [J].
BESRA, GS ;
KHOO, KH ;
MCNEIL, MR ;
DELL, A ;
MORRIS, HR ;
BRENNAN, PJ .
BIOCHEMISTRY, 1995, 34 (13) :4257-4266
[4]   STEREOSELECTIVE SYNTHESIS OF (+)-HYDANTOCIDIN [J].
CHEMLA, P .
TETRAHEDRON LETTERS, 1993, 34 (46) :7391-7394
[5]  
DAFFE M, 1990, J BIOL CHEM, V265, P6734
[6]   Ciprofloxacin - An updated review of its pharmacology, therapeutic efficacy and tolerability [J].
Davis, R ;
Markham, A ;
Balfour, JA .
DRUGS, 1996, 51 (06) :1019-1074
[7]   Spirodiketopiperazines of mannofuranose:: carbopeptoid α-amino acid esters at the anomeric position of mannofuranose [J].
Estevez, JC ;
Burton, JW ;
Estevez, RJ ;
Ardron, H ;
Wormald, MR ;
Dwek, RA ;
Brown, D ;
Fleet, GWJ .
TETRAHEDRON-ASYMMETRY, 1998, 9 (12) :2137-2154
[8]   COMPARATIVE INVITRO ACTIVITIES OF CIPROFLOXACIN AND OTHER 4-QUINOLONES AGAINST MYCOBACTERIUM-TUBERCULOSIS AND MYCOBACTERIUM-INTRACELLULARE [J].
FENLON, CH ;
CYNAMON, MH .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1986, 29 (03) :386-388
[9]   SYNTHESIS OF (5S,8R,9R,10S)-8,9,10-TRIHYDROXY-2-THIOXO-1,6-DIOXA-3-AZASPIRO[4.5]DECANE FROM 1-AMINO-1-DEOXY-D-ARABINO-HEXULOSE [J].
FERNANDEZBOLANOS, J ;
LOPEZ, AB ;
MOTA, JF .
CARBOHYDRATE RESEARCH, 1990, 199 (02) :239-242
[10]  
Kandeel ZE, 1996, HETEROATOM CHEM, V7, P29
12