Spontaneous Downbeat Nystagmus in Anti-GAD-Antibody-Associated Paraneoplastic Syndrome

被引：0

作者：

Shivaram, Sumanth ^{[1
]}

Tallapalli, Ashok V. Reddy ^{[1
]}

Gupta, Manisha ^{[1
]}

Nashi, Saraswati ^{[1
]}

Kulkarni, Girish B. ^{[1
]}

Alladi, Suvarna ^{[1
]}

机构：

[1] Natl Inst Mental Hlth & Neurosci NIMHANS, Dept Neurol, Bengaluru, Karnataka, India

来源：

JOURNAL OF NEUROSCIENCES IN RURAL PRACTICE | 2022年 / 13卷 / 03期

关键词：

anti-GAD antibodies; downbeat nystagmus; GLUTAMIC-ACID DECARBOXYLASE; BRAIN-STEM;

D O I：

10.1055/s-0042-1749404

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Spontaneous downbeat nystagmus and ocular flutter are rare clinical signs. Such findings are commonly related to cerebellar pathology, predominantly ischemia. In a significant percentage of patients, the cause may not be found. If these signs are associated with ataxia, cognitive decline, and seizure, anti-glutamic acid decarboxylase-associated neurological syndrome must be suspected. Background history of tumor has to be enquired. Treatment with immune modulation helps in partial recovery of such cases.

引用

页码：546 / 549

页数：4

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