Nontuberculous Mycobacterial Infections in Cystic Fibrosis

被引:27
作者
Martiniano, Stacey L. [1 ]
Nick, Jerry A. [2 ]
机构
[1] Univ Colorado Denver, Sch Med, Childrens Hosp Colorado, Dept Pediat, Aurora, CO 80045 USA
[2] Univ Colorado Denver, Natl Jewish Hlth, Dept Med, Denver, CO 80206 USA
关键词
Cystic fibrosis; Nontuberculous mycobacteria; Atypical mycobacteria; Mycobacterium avium complex; Mycobacterium abscessus; LONG-TERM SURVIVORS; LUNG-DISEASE; CONTROLLED-TRIAL; ANTIMICROBIAL SUSCEPTIBILITY; PSEUDOMONAS-AERUGINOSA; MULTICENTER PREVALENCE; DECONTAMINATION METHOD; CLINICAL-SIGNIFICANCE; ABSCESSUS INFECTION; PULMONARY INFECTION;
D O I
10.1016/j.ccm.2014.11.003
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Nontuberculous mycobacteria (NTM) are important emerging cystic fibrosis (CF) pathogens. Factors including the steady aging of the CF population, the apparent increase of NTM in the environment, and the potential for patient-to-patient transmission, may contribute to increased acquisition. Diagnosis of NTM disease is challenging due to disease overlap; thus, comprehensive care of the CF patient must be optimized to assess the clinical impact of the NTM (indolent versus active), and to improve response to treatment. The development of a CF-specific approach to the diagnosis and treatment of NTM infection is a research priority for the CF community.
引用
收藏
页码:101 / 115
页数:15
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