The role of ankyrin and spectrin in membrane transport and domain formation

被引：117
作者：
De Matteis, MA
Morrow, JS
机构：
[1] Ist Ric Farmacol Mario Negri, Consorzio Mario Negri Sud, Dept Cell Biol & Oncol, I-66030 Santa Maria Imbaro, Italy
[2] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06510 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 1998年 / 10卷 / 04期
关键词：
D O I：
10.1016/S0955-0674(98)80071-9
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Recent discoveries reveal a Golgi-centric spectrin-ankyrin skeleton required for Golgi integrity and anterograde protein trafficking. Identification of specific functional domains in spectrin that mediate its association with motor proteins and the Golgi complex has allowed novel insights into the structure and function of the secretory pathway, and into how this process is controlled by ADP-ribosylation factor and phosphoinositides. Alternative models of Golgi spectrin function that have been recently proposed are reviewed.
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页码：542 / 549
页数：8
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