Pulmonary Hemorrhaging as a Fatal Complication of IgA Vasculitis

被引:6
作者
Miyoshi, Seigo [1 ]
Nagao, Tomoaki [1 ]
Kukida, Masayoshi [1 ]
Miyoshi, Ken-ichi [1 ]
Namba, Chika [2 ]
Kitazawa, Sohei [3 ]
Nakamura, Yukihiro [1 ]
Hamaguchi, Naohiko [1 ]
Higaki, Jitsuo [1 ]
机构
[1] Ehime Univ, Dept Cardiol Pulmonol Hypertens & Nephrol, Grad Sch Med, Matsuyama, Ehime, Japan
[2] Ehime Univ, Dept Dermatol, Grad Sch Med, Matsuyama, Ehime, Japan
[3] Ehime Univ, Dept Mol Pathol, Grad Sch Med, Matsuyama, Ehime, Japan
关键词
IgA vasculitis; pulmonary hemorrhaging; HENOCH-SCHONLEIN PURPURA; DIFFUSE ALVEOLAR HEMORRHAGE; ANAPHYLACTOID PURPURA; SCHOENLEIN PURPURA; ATYPICAL PRESENTATION; GLOMERULONEPHRITIS; INVOLVEMENT;
D O I
10.2169/internalmedicine.0817-18
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A 64-year-old man was admitted to our hospital for purpuric rash, joint pain, and a fever. He had earlier undergone a follow-up examination for interstitial lung disease. At the current visit, the diagnosis was immunoglobulin A (IgA) vasculitis, based on skin and renal biopsy findings. He developed sudden breathlessness and hemoptysis. Chest computed tomography revealed ground glass opacity in the right lower lung fields. suggesting pulmonary hemorrhaging associated with IgA vasculitis. Despite steroid and cyclophosphamide therapy, and plasma exchange, he died 52 days after admission. Early aggressive therapies may be recommended for old patients with IgA vasculitis who have an additional comorbidities.
引用
收藏
页码:3141 / 3147
页数:7
相关论文
共 42 条
[1]  
Aeschlimann FA, 2017, CASE REP NEPHROL DIA, V7, P73, DOI 10.1159/000477662
[2]   Henoch-Schonlein nephritis complicated with pulmonary hemorrhage but treated successfully [J].
Al-Harbi, NN .
PEDIATRIC NEPHROLOGY, 2002, 17 (09) :762-764
[3]   IgA vasculitis (Henoch-Shonlein purpura) in adults: Diagnostic and therapeutic aspects [J].
Audemard-Verger, Alexandra ;
Pillebout, Evangeline ;
Guillevin, Loic ;
Thervet, Eric ;
Terrier, Benjamin .
AUTOIMMUNITY REVIEWS, 2015, 14 (07) :579-585
[4]   Addition of Plasma Exchange to Glucocorticosteroids for the Treatment of Severe Henoch-Schonlein Purpura in Adults: A Case Series [J].
Augusto, Jean-Francois ;
Sayegh, Johnny ;
Delapierre, Laurence ;
Croue, Anne ;
Tollis, Frederic ;
Cousin, Maud ;
Subra, Jean-Francois .
AMERICAN JOURNAL OF KIDNEY DISEASES, 2012, 59 (05) :663-669
[5]   Pulmonary haemorrhage in a 6-year-old boy with Henoch-Schonlein purpura [J].
Besbas, N ;
Duzova, A ;
Topaloglu, R ;
Gok, F ;
Ozaltin, F ;
Ozen, S ;
Bakkaloglu, A .
CLINICAL RHEUMATOLOGY, 2001, 20 (04) :293-296
[6]  
Carter ER, 1996, WESTERN J MED, V164, P171
[7]  
CREAM J J, 1970, QJM, V39, P461
[8]   A 72-year-old man with a purpuric rash [J].
Goel, Sachin S. ;
Langford, Carol A. .
CLEVELAND CLINIC JOURNAL OF MEDICINE, 2009, 76 (06) :353-360
[9]   Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation [J].
Ito, Yuhei ;
Arita, Machiko ;
Kumagai, Shogo ;
Takei, Reoto ;
Noyama, Maki ;
Tokioka, Fumiaki ;
Nagamoto, Takumi ;
Kawakita, Chieko ;
Asano, Kenichiro ;
Okita, Chika ;
Ishida, Tadashi .
INTERNAL MEDICINE, 2018, 57 (01) :81-84
[10]   PULMONARY HEMORRHAGE AND DEATH COMPLICATING ANAPHYLACTOID PURPURA [J].
JACOME, AF .
SOUTHERN MEDICAL JOURNAL, 1967, 60 (09) :1003-&