One-pot synthesis of 2-amino-3-cyanopyridine derivatives under microwave irradiation without solvent

被引：99

作者：

Shi, F ^{[1
]}

Tu, SJ ^{[1
]}

Fang, F ^{[1
]}

Li, TJ ^{[1
]}

机构：

[1] Xuzhou Normal Univ, Dept Chem, Key Lab Biotechnol Med Plants, Xuzhou 221116, Jiangsu, Peoples R China

来源：

ARKIVOC | 2005年

关键词：

pyridine derivatives; one-pot synthesis; microwave irradiation; solvent-free;

D O I：

10.3998/ark.5550190.0006.114

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 2-amino-3-cyanopyridine derivatives have been prepared by one-pot condensation from malononitrile, aromatic aldehyde, methyl ketone and ammonium acetate under microwave irradiation without solvent. This method has the advantage of short routine, high yields and being environmentally-friendly.

引用

页码：137 / 142

页数：6

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