Prothrombin measurement using a patient self-testing system

被引:0
作者
Andrew, M
Ansell, JL
Becker, DM
Becker, RC
Triplett, DA
机构
[1] Ball Mem Hosp, Dept Res, Midwest Hemostasis & Thrombosis Labs, Muncie, IN 47303 USA
[2] Hamilton Civ Hosp Ctr, Hamilton, ON, Canada
[3] Hosp Sick Children, Toronto, ON M5G 1X8, Canada
[4] Boston Univ, Med Ctr, Boston, MA USA
[5] Univ Virginia, Med Ctr, Charlottesville, VA USA
[6] Univ Massachusetts, Mem Med Ctr, Thrombosis Res Ctr, Worcester, MA 01605 USA
关键词
prothrombin time; point-of-care testing; self-testing; anticoagulation;
D O I
暂无
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
We enrolled 82 patients receiving oral anticoagulation in a pilot trial of a point-of-care (POC) prothrombin time (PT) device in a patient self-testing (PST) application in 7 US and Canadian hospital-based anticoagulation centers. The properly selected and suitably trained patients were given the PT device to test at home for 6 weeks. Patients returned within 3 hours of the self-test to the hospital clinic where a repeated test was performed by a health care professional using the patient's POC device (clinic). Blood specimens were obtained for routine laboratory PT determinations by the local hospital laboratory (hospital) and a reference laboratory International Normalized Ratio agreement between the home test and the clinic test was excellent. Home results correlated well with reference laboratory results. Using the I reference laboratory as a standard, 68% of hospital and 66% of home results matched the patient's therapeutic range classification of the reference laboratory result. Participants overwhelmingly reported satisfaction and willingness to perform the self-test. Our results confirm the equivalence of the PST PT and a reference laboratory result and suggest that PST PT technology is an appropriate and useful adjunct to routine oral anticoagulation monitoring methods.
引用
收藏
页码:280 / 287
页数:8
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