The past, present and future of protein-based materials

被引:81
作者
Abascal, Nadia C. [1 ]
Regan, Lynne [2 ,3 ]
机构
[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT USA
[2] Univ Edinburgh, Inst Quantitat Biol Biochem & Biotechnol, Dept Interdisciplinary Sci, Ctr Synthet & Syst Biol,Sch Biol Sci, Edinburgh, Midlothian, Scotland
[3] Yale Univ, Integrated Grad Program Phys & Engn Biol, Dept Chem, 225 Prospect St, New Haven, CT 06520 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
protein-based materials; recombinant proteins; biomaterials; drug delivery; ELASTIN-LIKE POLYPEPTIDES; SILK; RESILIN; COLLAGEN; DESIGN; MODEL; TROPOELASTIN; POLYMERS; FILMS;
D O I
10.1098/rsob.180113
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Protein-based materials are finding new uses and applications after millennia of impacting the daily life of humans. Some of the earliest uses of protein-based materials are still evident in silk and wool textiles and leather goods. Today, even as silks, wools and leathers are still be used in traditional ways, these proteins are now seen as promising materials for biomaterials, vehicles of drug delivery and components of high-tech fabrics. With the advent of biosynthetic methods and streamlined means of protein purification, protein-based materials-recombinant and otherwise-are being used in a host of applications at the cutting edge of medicine, electronics, materials science and even fashion. This commentary aims to discuss a handful of these applications while taking a critical look at where protein-based materials may be used in the future.
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页数:8
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