Production of free standing composite membranes or of patterned films after sol-gel reactions in an exponential layer-by-layer architecture

被引:8
作者
Zouari, Riadh [2 ]
Michel, Marc [3 ]
Di Martino, Jean [3 ]
Ball, Vincent [1 ,4 ]
机构
[1] INSERM, UMR 977, F-67085 Strasbourg, France
[2] CNRS, Inst Charles Sadron, Unite Propre Rech 22, F-67034 Strasbourg, France
[3] Ctr Rech Publ Paul Tudor, L-4002 Esch Sur Alzette, Luxembourg
[4] Univ Strasbourg, Fac Chirurg Dent, F-67000 Strasbourg, France
来源
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2010年 / 30卷 / 08期
关键词
Silica; Titania; Polyelectrolyte multilayer films; Free standing films; Self patterned films; POLYELECTROLYTE MULTILAYER FILMS; CROSS-LINKING; THIN-FILM; NANOPARTICLES; STABILITY; COATINGS; GROWTH; IONS;
D O I
10.1016/j.msec.2010.07.017
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
This paper aims at describing that polyelectrolyte multilayer (PEM) films, made of biocompatible molecules, Hyaluronic acid (HA) and Poly(6-lysine) (PLL), can entrap negatively charged precursors of titania or silica. These precursors undergo hydrolysis and polycondensation in contact with the amino groups of PLL leading to the formation of oxides (TiO(2) or SiO(2)) within the films. Moreover, this work shows that these composite thin films, a few mu m thick, can be easily detached as free standing membranes containing photoactive TiO(2). To this aim the PEM film containing TiO(2) was thermally cross-linked to form amide bonds. Immersion of the film in diluted hydrofluoric acid (2% (v/v)) allowed then the formation of a free standing membrane. We extend the concept of sol-gel reaction in PEM films to films made from poly(L-glutamic acid) (PGA) and Poly (allylamine) (PAH) and show that the composition of the multilayer film influences the distribution of the inorganic material in the films: the TiO(2) distribution seems homogeneous in (PLL-HA)(n) films whereas the (PAH-PGA)(n) films are self patterned with inorganic aggregates tens of micrometers in diameter. The free standing membranes or self patterned composite films obtained in this investigation may present interesting bio-applications. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:1291 / 1297
页数:7
相关论文
共 32 条
[1]   Nanoengineering of inorganic and hybrid hollow spheres by colloidal templating [J].
Caruso, F ;
Caruso, RA ;
Möhwald, H .
SCIENCE, 1998, 282 (5391) :1111-1114
[2]   Freestanding ultrathin nano-membranes via self-assembly [J].
Cheng, Wenlong ;
Campolongo, Michael J. ;
Tan, Shawn J. ;
Luo, Dan .
NANO TODAY, 2009, 4 (06) :482-493
[3]   Interactions of amino-containing peptides with sodium silicate and colloidal silica: A biomimetic approach of silicification [J].
Coradin, T ;
Durupthy, O ;
Livage, J .
LANGMUIR, 2002, 18 (06) :2331-2336
[4]  
Dai JH, 2002, NANO LETT, V2, P497, DOI [10.1021/nl025547l, 10.1021/nl0255471]
[5]   Fuzzy nanoassemblies: Toward layered polymeric multicomposites [J].
Decher, G .
SCIENCE, 1997, 277 (5330) :1232-1237
[6]   Tissue cells feel and respond to the stiffness of their substrate [J].
Discher, DE ;
Janmey, P ;
Wang, YL .
SCIENCE, 2005, 310 (5751) :1139-1143
[7]  
Donath E, 1998, ANGEW CHEM INT EDIT, V37, P2202, DOI 10.1002/(SICI)1521-3773(19980904)37:16<2201::AID-ANIE2201>3.0.CO
[8]  
2-E
[9]   Multicompartment films made of alternate polyelectrolyte multilayers of exponential and linear growth [J].
Garza, JM ;
Schaaf, P ;
Muller, S ;
Ball, V ;
Stoltz, JF ;
Voegel, JC ;
Lavalle, P .
LANGMUIR, 2004, 20 (17) :7298-7302
[10]   Synthesis of passivating, nylon-like coatings through cross-linking of ultrathin polyelectrolyte films [J].
Harris, JJ ;
DeRose, PM ;
Bruening, ML .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (09) :1978-1979