Acquired colour deficiency in patients with Parkinson's disease

被引:35
作者
Birch, J
Kolle, RU
Kunkel, M
Paulus, W
Upadhyay, P
机构
[1] City Univ London, Dept Optometry & Visual Sci, Appl Vis Res Lab, London EC1V 7DD, England
[2] Univ Gottingen, Dept Clin Neurophysiol, D-3400 Gottingen, Germany
[3] Univ New S Wales, Sch Optometry, Sydney, NSW, Australia
关键词
colour deficiency; Parkinson's disease; clinical tests; tritan tests;
D O I
10.1016/S0042-6989(97)00398-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The blue cone pathway is reported to be affected early in Parkinson's disease (PD) and acquired type three (tritan) defects may occur. Sixty-one patients attending a treatment and rehabilitation centre for PD were examined with clinical colour vision tests. Seven of 13 patients, for whom the diagnosis of PD was equivocal or who had other medical conditions, were identified as having tritan colour deficiency. Results for the remaining 44 PD patients were compared with 40 age matched controls. Ten PD patients (22.7%) had tritan defects. Tritan defects were not found in the control group but performance on some tests was age related. We conclude that clinical tests for tritan colour deficiency are unlikely to be helpful in identifying PD. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:3421 / 3426
页数:6
相关论文
共 10 条
[1]  
BIRCH J, 1980, COLOUR DEFICIENCIES, P83
[2]  
Birch J., 1993, DIAGNOSIS DEFECTIVE
[3]  
BIRCH J, 1997, J DALTONS COLOUR VIS, P309
[4]   L-DOPA IMPROVES COLOR-VISION IN PARKINSONS-DISEASE [J].
BUTTNER, T ;
KUHN, W ;
PATZOLD, T ;
PRZUNTEK, H .
JOURNAL OF NEURAL TRANSMISSION-PARKINSONS DISEASE AND DEMENTIA SECTION, 1994, 7 (01) :13-19
[5]   DISTORTED COLOR DISCRIMINATION IN DE-NOVO PARKINSONIAN-PATIENTS [J].
BUTTNER, T ;
KUHN, W ;
MULLER, T ;
PATZOLD, T ;
HEIDBRINK, K ;
PRZUNTEK, H .
NEUROLOGY, 1995, 45 (02) :386-387
[6]   IMPAIRED COLOR DISCRIMINATION IN PARKINSONS-DISEASE [J].
BUTTNER, T ;
PATZOLD, T ;
KUHN, W ;
MULLER, T ;
PRZUNTEK, H .
NEURO-OPHTHALMOLOGY, 1994, 14 (02) :91-95
[7]   PREDOMINANT AFFECTION OF THE BLUE CONE PATHWAY IN PARKINSONS-DISEASE [J].
HAUG, BA ;
KOLLE, RU ;
TRENKWALDER, C ;
OERTEL, WH ;
PAULUS, W .
BRAIN, 1995, 118 :771-778
[8]   VISUAL THRESHOLDS TO LOW-CONTRAST PATTERN DISPLACEMENT, COLOR CONTRAST, AND LUMINANCE CONTRAST STIMULI IN PARKINSONS-DISEASE [J].
HAUG, BA ;
TRENKWALDER, C ;
ARDEN, GB ;
OERTEL, WH ;
PAULUS, W .
MOVEMENT DISORDERS, 1994, 9 (05) :563-570
[9]   VISUAL-SYSTEM ABNORMALITIES IN PATIENTS WITH PARKINSONS-DISEASE [J].
KUPERSMITH, MJ ;
SHAKIN, E ;
SIEGEL, IM ;
LIEBERMAN, A .
ARCHIVES OF NEUROLOGY, 1982, 39 (05) :284-286
[10]   ABNORMALITIES IN COLOR-VISION AND CONTRAST SENSITIVITY IN PARKINSONS-DISEASE [J].
PRICE, MJ ;
FELDMAN, RG ;
ADELBERG, D ;
KAYNE, H .
NEUROLOGY, 1992, 42 (04) :887-890