Lower prevalence of congenital cytomegalovirus infection in Portugal: possible impact of COVID-19 lockdown?

被引：14

作者：

Fernandez, Catarina ^{[1
]}

Chasqueira, Maria-Jesus ^{[1
]}

Marques, Augusta ^{[1
]}

Rodrigues, Lucia ^{[1
]}

Marcal, Monica ^{[2
]}

Tuna, Madalena ^{[2
]}

Braz, Monica Cro ^{[3
]}

Neto, Ana Serrao ^{[3
]}

Mendes, Candida ^{[4
]}

Lito, David ^{[4
]}

Rocha, Paula ^{[5
]}

Vasconcellos, Gabriela ^{[5
]}

Menezes, Maria-Favila ^{[6
]}

Sousa, Maria Jose ^{[6
]}

Nunes, Carla ^{[7
]}

Paixao, Paulo ^{[1
]}

机构：

[1] CEDOC, NOVA Med Sch, Fac Ciencias Med, Ctr Estudos Doencas Cron, Campo Martires da Patria 130, P-1169056 Lisbon, Portugal

[2] Hosp Sao Francisco Xavier CHLO, Unidade Neonatol Serv Pediat, Estr Forte Alto Duque, P-1449005 Lisbon, Portugal

[3] Hosp CUF Descobertas, Serv Pediat, Rua Mario Botas, P-1998018 Lisbon, Portugal

[4] Hosp Vila Franca de Xira, Serv Pediat, Estr Carlos Lima Costa 2, P-2600009 Vila Franca De Xira, Portugal

[5] Hosp CUF Porto, Serv Pediat, Estr Circunvalacao 14341, P-4100180 Porto, Portugal

[6] Ctr Med Lab Germano Sousa, Rua Cupertino de Miranda, P-1600513 Lisbon, Portugal

[7] Univ NOVA Lisboa, Escola Nacl Saude Publ, Ctr Invest Saude Publ, Ave Padre Cruz, P-1600560 Lisbon, Portugal

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 2022年 / 181卷 / 03期

关键词：

COVID-19; CMV; Congenital; Screening; Pools;

D O I：

10.1007/s00431-021-04271-0

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Cytomegalovirus (CMV) is the most frequent cause of congenital infection all over the world. Its prevalence ranges from 0.2 to 2.2%. Transmission from children to their pregnant mothers is a well-known risk factor, particularly if they attend a childcare centre. This study aims to compare the prevalence of CMV congenital infection (CMV_CI) in Portugal (Lisbon) between two studies, performed respectively in 2019 and 2020. In the 2019 study, performed in two hospitals, we found a 0.67% CMV_CI prevalence, using a pool strategy previously tested with saliva samples. In the 2020 study, using the same pool approach in four hospitals (the previous and two additional), and based on 1277 samples, the prevalence was 0.078%. Conclusion: The close temporal coincidence with COVID-19 lockdown suggests that these measures may have had a significant impact on this reduction, although other explanations cannot be ruled-out.

引用

页码：1259 / 1262

页数：4

共 15 条

[1] Effects of COVID-19 lockdown on epidemic diseases of childhood [J].