Myeloproliferative Disorders and the Hyperviscosity Syndrome

被引：20

作者：

Adams, Bruce D. ^{[1
,2
]}

Baker, Russell ^{[3
]}

Lopez, J. Abraham ^{[3
]}

Spencer, Susan ^{[3
]}

机构：

[1] William Beaumont Army Med Ctr, Dept Clin Invest, El Paso, TX 79920 USA

[2] Med Coll Georgia, Dept Emergency Med, Augusta, GA 30912 USA

[3] Texas Tech Univ Heath Sci Ctr, Dept Emergency Med, Paul L Foster Sch Med, El Paso, TX 79905 USA

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2010年 / 24卷 / 03期

关键词：

Hyperviscosity syndrome; Essential thrombocytosis; Hyperleukocytosis; Leukostasis; Polycythemia vera; Waldenstrom macroglobulinemia; ACUTE MYELOID-LEUKEMIA; ORGANIZATION DIAGNOSTIC-CRITERIA; ACUTE MYELOGENOUS LEUKEMIA; POLYCYTHEMIA-VERA; ESSENTIAL THROMBOCYTHEMIA; WALDENSTROM MACROGLOBULINEMIA; MULTIPLE-MYELOMA; THERAPEUTIC APHERESIS; IDIOPATHIC ERYTHROCYTOSIS; ONCOLOGIC EMERGENCIES;

D O I：

10.1016/j.hoc.2010.03.004

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Myeloproliferative disorders and the serum hyperviscosity syndrome can rapidly manifest with emergent presentations. Hyperviscosity occurs from pathologic elevations of either the cellular or acellular (protein) fractions of the circulating blood. Classic hyperviscosity syndrome presents with the triad of bleeding diathesis, visual disturbances, and focal neurologic signs. Emergency medicine providers should be aware of these conditions and be prepared to rapidly initiate supportive and early definitive management, including plasma exchange and apharesis. Early consultation with a hematologist is essential to managing these complex patients.

引用

页码：585 / +

页数：19

共 114 条

[1]

Athale UH, 2007, SEMIN THROMB HEMOST, V33, P408, DOI 10.1055/s-2007-976176

[2] Acute monocytic leukemia presenting as acute respiratory failure [J].

Azoulay, É ;

Fieux, F ;

Moreau, D ;

Thiery, G ;

Rousselot, P ;

Parrot, A ;

Le Gall, JR ;

Dombret, H ;

Schlemmer, B .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2003, 167 (10) :1329-1333

[3] Current concepts: Diagnosis from the blood smear [J].

Bain, BJ .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (05) :498-507

[4] Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the international working group for myelofibrosis research and treatment [J].

Barosi, G. ;

Mesa, R. A. ;

Thiele, J. ;

Cervantes, F. ;

Campbell, P. J. ;

Verstovsek, S. ;

Dupriez, B. ;

Levine, R. L. ;

Passamonti, F. ;

Gotlib, J. ;

Reilly, J. T. ;

Vannucchi, A. M. ;

Hanson, C. A. ;

Solberg, L. A. ;

Orazi, A. ;

Tefferi, A. .

LEUKEMIA, 2008, 22 (02) :437-438

[5]

Bekelman J., 2006, OSLER MED HDB

[6] Therapeutic apheresis in hyperleukocytosis and hyperviscosity syndrome [J].

Blum, William ;

Porcu, Pierluigi .

SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2007, 33 (04) :350-354

[7] Essential thrombocythemia [J].

Briere, Jean B. .

ORPHANET JOURNAL OF RARE DISEASES, 2007, 2 (1)

[8]

BUCHEM MA, 1988, ANN HEMATOL, V56, P39

[9] Impact of leukapheresis on early death rate in adult acute myeloid leukemia presenting with hyperleukocytosis [J].

Bug, Gesine ;

Anargyrou, Konstantinos ;

Tonn, Torsten ;

Bialleck, Heike ;

Seifried, Erhard ;

Hoelzer, Dieter ;

Ottmann, Oliver G. .

TRANSFUSION, 2007, 47 (10) :1843-1850

[10]

Burwick N, 2008, CURR OPIN INVEST DR, V9, P631

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