Regulatory T Cells under the Mercy of Mitochondria

被引：14

作者：

Das, Mrinmoy ^{[1
]}

Alzaid, Fawaz ^{[2
]}

Bayry, Jagadeesh ^{[2
]}

机构：

[1] Harvard Med Sch, Boston Childrens Hosp, Div Immunol, Boston, MA 02115 USA

[2] Univ Paris 05, Sorbonne Univ, Sorbonne Paris Cite, INSERM,Ctr Rech Cordeliers, F-75006 Paris, France

来源：

CELL METABOLISM | 2019年 / 29卷 / 02期

关键词：

MUTATIONS;

D O I：

10.1016/j.cmet.2019.01.012

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mitochondria, the powerhouse of the cell, known for producing energy through oxidative phosphorylation and the Krebs cycle, continue gaining notoriety for roles beyond bioenergetics. Recently in Nature, Weinberg et al. (2019) reported that mitochondrial complex III is indispensable for suppressive function of regulatory T cells, thus highlighting the importance of mitochondria in immune tolerance.

引用

页码：243 / 245

页数：3

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