Synthesis of α-fluoroalkyl substituted peptides via enzymatic fragment condensation

被引：28
作者：
Bordusa, F
Dahl, C
Jakubke, HD
Burger, K
Koksch, B
机构：
[1] Univ Leipzig, Dept Biochem, D-04103 Leipzig, Germany
[2] Univ Leipzig, Dept Organ Chem, D-04103 Leipzig, Germany
来源：
TETRAHEDRON-ASYMMETRY | 1999年 / 10卷 / 02期
关键词：
D O I：
10.1016/S0957-4166(98)00508-4
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A peptide library consisting of di- and tripeptide esters and tripeptide amides, respectively, containing alpha-Tfm amino acids in different positions was synthesized and tested for enzymatic fragment condensations catalyzed by the proteases alpha-chymotrypsin, trypsin and clostripain. (C) 1999 Elsevier Science Ltd. All rights reserved.
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页码：307 / 313
页数：7
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