Ovarian salvage in bilaterally complicated severe ovarian hyperstimulation syndrome

Objective: To report the management of 2 cases of severe ovarian hyperstimulation syndrome (OHSS) bilaterally complicated by rupture and late subsequent torsion. Design: Two case reports. Setting: Obstetrics and Gynecology department of a hospital. Patient(s): Case 1: Severe OHSS complicated by massive intraperitoneal hemorrhage and bilateral extensive ovarian rents and rupture at multiple sites. Case 2: Twin IVF pregnancy and late severe OHSS complicated further by subsequent bilateral torsion. Intervention(s): Case 1: Diagnosed by clinical, hematologic, and ultrasound findings. Resuscitation, laparotomy, and meticulous ovarian repair with suture, glue, and hemostat affected bilateral ovarian conservation. Case 2: Diagnosed clinically and confirmed by color Doppler. Left salpingoopherectomy was performed because of a devitalized left ovary; 3 days later laparoscopic right ovarian detorsion and aspiration was possible as early Doppler diagnosis was made. Main Outcome Measure(s): Case 1: ovarian conservation. Case 2: ovarian conservation and continuation of pregnancy. Result(s): Case 1: Recovery and normal serum FSH and E-2 2 months postsurgery. Case 2: Continuation of pregnancy and the remaining ovary was healthy at abdominal delivery. Conclusion(s): Two cases of bilaterally complicated severe OHSS in which the patients' safety and bilateral ovarian integrity were at jeopardy. The cases are presented to define the importance of awareness, early diagnosis, and intervention, as well as the use of various methods and techniques to affect preservation of ovarian integrity and reserve. (Fertil Steril (R) 2011; 96: e77-9. (C) 2011 by American Society for Reproductive Medicine.)