Molecular mechanisms of T-cell exhaustion and implications for immunotherapy.

被引:0
|
作者
Wherry, E. John [1 ]
机构
[1] Univ Penn, Philadelphia, PA 19104 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
IA17
引用
收藏
页码:21 / 21
页数:1
相关论文
共 50 条
  • [21] T-cell exhaustion
    Bradbury, Jane
    LANCET INFECTIOUS DISEASES, 2013, 13 (06): : 483 - 483
  • [22] Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations
    Tabana, Yasser
    Moon, Tae Chul
    Siraki, Arno
    Elahi, Shokrollah
    Barakat, Khaled
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2021, 25 (05) : 347 - 363
  • [23] Overcoming T-cell exhaustion: new therapeutic targets in HCC immunotherapy
    Seimiya, Takahiro
    Otsuka, Motoyuki
    Fujishiro, Mitsuhiro
    HEPATOLOGY, 2023, 78 (04) : 1009 - 1011
  • [24] Mechanisms of T cell exhaustion guiding next-generation immunotherapy
    Zebley, Caitlin C.
    Youngblood, Ben
    TRENDS IN CANCER, 2022, 8 (09) : 726 - 734
  • [25] Specific increase in T-cell potency via structure-based design of a T-cell receptor for adoptive immunotherapy.
    Malecek, Karolina
    Grigoryan, Arsen
    Zhong, Shi
    Gu, Wei Jun
    Johnson, Laura A.
    Rosenberg, Steven A.
    Cardozo, Timothy
    Krogsgaard, Michelle
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [26] ANERGY AND EXHAUSTION ARE INDEPENDENT MECHANISMS OF PERIPHERAL T-CELL TOLERANCE
    ROCHA, B
    GRANDIEN, A
    FREITAS, AA
    JOURNAL OF EXPERIMENTAL MEDICINE, 1995, 181 (03): : 993 - 1003
  • [27] The T-cell repertoire as a biomarker for response to anti PD-1 immunotherapy.
    Philip, Hagit
    Snir, Tom
    Gordin, Miri
    Wigelman, Yoav
    Zilberberg, Alona
    Efroni, Sol
    CANCER IMMUNOLOGY RESEARCH, 2020, 8 (03) : 105 - 105
  • [28] Generation of autologous T cell responses against CLL cells: Implications for immunotherapy.
    Krackhardt, A
    Trojan, A
    Gribben, JG
    BLOOD, 1999, 94 (10) : 601A - 601A
  • [29] Deciphering Regulatory T-Cell Dynamics in Cancer Immunotherapy: Mechanisms, Implications, and Therapeutic Innovations
    Bhattacharya, Sankha
    Paraskar, Gaurav
    Jha, Megha
    Gupta, Girdhari Lal
    Prajapati, Bhupendra G.
    ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE, 2024, 7 (08) : 2215 - 2236
  • [30] Molecular mechanisms of T-cell anergy
    E. M. Kuklina
    Biochemistry (Moscow), 2013, 78 : 144 - 156