Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer

被引:11
作者
Miles, Anne [1 ]
Evans, Ruth E. C. [1 ]
Halligan, Steve [2 ]
Beare, Sandy [3 ]
Bridgewater, John [4 ]
Goh, Vicky [5 ]
Janes, Sam M. [6 ]
Navani, Neal [7 ]
Oliver, Alfred [8 ]
Morton, Alison [8 ]
Morris, Steve [9 ]
Rockall, Andrea [10 ]
Taylor, Stuart A. [2 ]
机构
[1] Birkbeck Univ London, Dept Psychol Sci, Malet St, London WC1E 7HX, England
[2] UCL, Ctr Med Imaging, Charles Bell House, London, England
[3] UCL, Canc Res UK, Clin Trials Ctr, London, England
[4] UCL Canc Inst, Paul O Gorman Bldg, London, England
[5] Kings Coll London, Sch Biomed Engn & Imaging Sci, Canc Imaging, London, England
[6] UCL, Lungs Living Res Ctr, Div Med, UCL Resp, London, England
[7] UCL, UCLH & Lungs Living Res Ctr, Dept Thorac Med, UCL Resp, London, England
[8] Natl Canc Res Inst, Canc Patient Representat, London, England
[9] UCL, Res Dept Appl Hlth Res, London, England
[10] Imperial Coll London, Dept Surg & Canc, London, England
基金
美国国家卫生研究院;
关键词
cancer; magnetic resonance imaging; patient preference; positron emission tomography; tomography; X-ray computed; NEGATIVE AFFECT; VALIDITY; RISKS; PANAS; CARE;
D O I
10.1111/1754-9485.13038
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Introduction Whole body magnetic resonance imaging (WB-MRI) may be more efficient in staging cancers, but can be harder for patients to tolerate. We examined predictors of patient preference for WB-MRI vs. CT/ PET-CT for staging colorectal or lung cancer. Methods Patients recruited prospectively to two multicentre trials comparing diagnostic accuracy of WB-MRI with standard staging scans were sent two questionnaires: the first, administered at trial registration, captured demographics, educational level and comorbidities; the second, administered after staging completion, measured emotional distress (GHQ-12), positive mood (PANAS), perceived scan burden, patients' beliefs about WB-MRI, and preference for either WB-MRI or CT (colorectal trial), WB-MRI or PET-CT (lung trial). Preference for WB-MRI or CT/ PET-CT was analysed using logistic regression. Results Baseline and post-staging questionnaires were completed by 97 and 107 patients, respectively. Overall, 56/107 (52%) preferred WB-MRI over standard scans and were more likely to have no additional comorbidities, higher positive mood, greater awareness of potential benefits of WB-MRI and lower levels of perceived WB-MRI scan burden. In adjusted analyses, only awareness of potential WB-MRI benefits remained a significant predictor (OR: 1.516, 95% CIs 1.006-2.284, P = 0.047). Knowledge that WB-MRI does not use radiation predicted preference (adjusted OR: 3.018, 95% CIs 1.099-8.288, P = 0.032), although only 45/107 (42%) patients were aware of this attribute. Conclusions A small majority of patients undergoing staging of colorectal or lung cancer prefer WB-MRI to CT/ PET-CT. Raising awareness of the potential benefits of WB-MRI, notably lack of ionizing radiation, could influence preference.
引用
收藏
页码:537 / 545
页数:9
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