SIDE EFFECTS OF THE IMMUNE SYSTEM: LESSONS FROM TUBERCULOSIS-RELATED IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME

被引：0
作者：
Buonsenso, D. [1 ]
Pirronti, T. [2 ]
Genovese, O. [3 ]
Gargiullo, L. [1 ]
Ranno, O. [1 ]
Valentini, P. [1 ]
机构：
[1] Univ Cattolica Sacro Cuore, A Gemelli Hosp, Dept Pediat, I-00168 Rome, Italy
[2] Univ Cattolica Sacro Cuore, A Gemelli Hosp, Dept Bioimaging & Radiol Sci, I-00168 Rome, Italy
[3] Univ Cattolica Sacro Cuore, A Gemelli Hosp, Dept Anesthesiol & Intens Care, I-00168 Rome, Italy
来源：
EUROPEAN JOURNAL OF INFLAMMATION | 2012年 / 10卷 / 01期
关键词：
IRIS; TB; HIV; immune system; ACTIVE ANTIRETROVIRAL THERAPY; VIRUS-INFECTED CHILDREN; MYCOBACTERIUM-TUBERCULOSIS; UGANDAN CHILDREN; HIV-INFECTION; T-CELLS; MACROPHAGES; EXPRESSION; GRANULOMAS; BIOMARKERS;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Immune reconstitution inflammatory syndrome (IRIS) is a recently described syndrome among human immunodeficiency virus (HIV)-infected patients attributable to the recovery of the immune system during antiretroviral therapy. A growing number of researches on this syndrome have been conducted in recent years, but IRIS in children has not been widely studied. We report the case of a 4.5 month-old, tuberculosis (TB)-HIV co-infected girl who developed IRIS two months after beginning antiretroviral and anti-TB medications. We moreover review the immunopathogenesis of TB-HIV coinfection and IRIS, with particular regard to TB-related IRIS.
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页码：1 / 10
页数：10
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