Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration

被引：31

作者：

Atia, Gamal Abdel Nasser ^{[1
]}

Shalaby, Hany K. ^{[2
]}

Zehravi, Mehrukh ^{[3
]}

Ghobashy, Mohamed Mohamady ^{[4
]}

Attia, Hager Abdel Nasser ^{[5
]}

Ahmad, Zubair ^{[6
,7
]}

Khan, Farhat S. ^{[7
]}

Dey, Abhijit ^{[8
]}

Mukerjee, Nobendu ^{[9
,10
]}

Alexiou, Athanasios ^{[10
]}

Rahman, Md. Habibur ^{[11
]}

Klepacka, Joanna ^{[12
]}

Najda, Agnieszka ^{[13
]}

机构：

[1] Suez Canal Univ, Dept Oral Med Periodontol & Diag, Fac Dent, POB 41522, Ismailia 41522, Egypt

[2] Suez Univ, Dept Oral Med Periodontol & Oral Diag, Fac Dent, POB 43512, Suez, Egypt

[3] Prince Sattam Bin Abdul Aziz Univ, Dept Clin Pharm, Girls Sect, Al Kharj 11942, Saudi Arabia

[4] Natl Ctr Radiat Res & Technol NCRRT, Radiat Res Polymer Chem Dept, Atom Energy Author, POB 13759, Cairo, Egypt

[5] Alexandria Univ, Fac Sci, Dept Mol Biol & Chem, POB 21526, Alexandria, Egypt

[6] King Khalid Univ, Fac Sci, Unit Bee Res & Honey Prod, POB 9004, Abha 61413, Saudi Arabia

[7] King Khalid Univ, Dept Biol, Coll Arts & Sci, POB 9004, Abha 61413, Saudi Arabia

[8] Presidency Univ, Dept Life Sci, Kolkata 700073, India

[9] Ramakrishna Mission Vivekananda Centenary Coll, Dept Microbiol, Khardaha 700118, India

[10] Novel Global Community Educ Fdn, Dept Sci & Engn, Hebersham, NSW 2770, Australia

[11] Yonsei Univ, Wonju Coll Med, Dept Global Med Sci, Wonju 26426, South Korea

[12] Univ Warmia & Mazury, Fac Food Sci, Dept Commod Sci & Food Anal, Oczapowskiego 2, PL-10719 Olsztyn, Poland

[13] Univ Life Sci Lublin, Dept Vegetable & Herbal Crops, Doswiadczalna St 51A, PL-20280 Lublin, Poland

来源：

POLYMERS | 2022年 / 14卷 / 15期

关键词：

chitosan; periodontitis; scaffold; regeneration; tissue engineering; ENDOTHELIAL GROWTH-FACTOR; CONTROLLED-RELEASE; BONE-FORMATION; IN-VITRO; BIOMEDICAL APPLICATIONS; CLINDAMYCIN PHOSPHATE; DELIVERY-SYSTEMS; ERYTHROPOIETIN; NANOPARTICLES; DOXYCYCLINE;

D O I：

10.3390/polym14153192

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Chitosan is a natural anionic polysaccharide with a changeable architecture and an abundance of functional groups; in addition, it can be converted into various shapes and sizes, making it appropriate for a variety of applications. This article examined and summarized current developments in chitosan-based materials, with a focus on the modification of chitosan, and presented an abundance of information about the fabrication and use of chitosan-derived products in periodontal regeneration. Numerous preparation and modification techniques for enhancing chitosan performance, as well as the uses of chitosan and its metabolites, were reviewed critically and discussed in depth in this study. Chitosan-based products may be formed into different shapes and sizes, considering fibers, nanostructures, gels, membranes, and hydrogels. Various drug-loaded chitosan devices were discussed regarding periodontal regeneration.

引用

页数：24

共 193 条

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