Diagnostic value of sural nerve matrix metalloproteinase-9 in diabetic patients with CIDP

被引：46
作者：
Jann, S
Bramerio, MA
Beretta, S
Koch, S
Defanti, CA
Toyka, KV
Sommer, C
机构：
[1] Univ Wurzburg, Neurol Klin, Dept Neurol, D-97080 Wurzburg, Germany
[2] Vimercate Hosp, Dept Neurol, Milan, Italy
[3] Niguarda Hosp, Dept Neurol, Milan, Italy
[4] Niguarda Hosp, Dept Pathol, Milan, Italy
来源：
NEUROLOGY | 2003年 / 61卷 / 11期
关键词：
D O I：
10.1212/01.WNL.0000096174.86850.7F
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Patients with diabetes mellitus (DM) may develop chronic inflammatory demyelinating polyneuropathy ( CIDP), which may be difficult to distinguish from diabetic neuropathy (DNP). Here the authors show that immunoreactivity for matrix metalloproteinase-9 on sural nerve biopsies may help to identify CIDP-DM. In a pilot study on 10 CIDP-DM patients with IV immunoglobulins and tight glycemic control, the CIDP-DM patients had a better outcome than DNP patients treated with tight glycemic control only.
引用
收藏
页码：1607 / 1610
页数：5
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