Transition metal-mediated N-heterocyclisation reactions. Synthesis of 2-phenylindole by reduction by CO of 2-nitrostilbene catalysed by [Rh(CO)(4)](-)

被引：12

作者：

Ragaini, F

Tollari, S

Cenini, S

Bettetini, E

机构：

[1] DIPARTIMENTO CHIM INORGAN MET ORGAN & ANALIT,I-20133 MILAN,ITALY

[2] CTR CNR,I-20133 MILAN,ITALY

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1996年 / 111卷 / 1-2期

关键词：

indoles; organic nitro compounds; rhodium; rhodium tetracarbonyl anion; homogeneous catalysis; heterocycles; N-heterocyclisation reactions;

D O I：

10.1016/1381-1169(96)00209-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The complex [PPN][Rh(CO)(4)] is a very efficient catalyst for the conversion of 2-nitrostilbene to 2-phenylindole by reduction by CO followed by cyclisation. The reaction is quite selective (up to 85%) and the only observable by-product is the amine corresponding to the starting material. The addition of 2-hydroxypyridine increases both conversion and selectivity. but simple pyridine deactivates the catalytic system. The reaction conditions have been optimised.

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页码：91 / 96

页数：6

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