Plasma deposited metal Schiff-base compounds as antimicrobials

被引：44

作者：

Poulter, Neil ^{[1
]}

Donaldson, Matthew ^{[1
]}

Mulley, Geraldine ^{[1
,2
]}

Duque, Luis ^{[1
]}

Waterfield, Nicholas ^{[2
]}

Shard, Alex G. ^{[3
]}

Spencer, Steve ^{[3
]}

Jenkins, A. Tobias A. ^{[1
]}

Johnson, Andrew L. ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England

[3] Natl Phys Lab, Teddington TW11 0LW, Middx, England

来源：

NEW JOURNAL OF CHEMISTRY | 2011年 / 35卷 / 07期

关键词：

RESISTANT STAPHYLOCOCCUS-AUREUS; QUATERNARY AMMONIUM; IN-VITRO; COMPLEXES; ZINC(II); CRYSTAL; ANTIBACTERIAL; CONTAMINATION; ENVIRONMENT; NICKEL(II);

D O I：

10.1039/c1nj20091g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

This paper details the synthesis, characterisation including crystal structure, and testing for antimicrobial efficacy of two compounds: a zinc centred bis(N-allylsalicylideneiminato)-zinc (ZSB) and its known copper analogue, bis(N-allylsalicylideneiminato)-copper (CSB). Differences in antimicrobial efficacy of the two compounds were observed, suggesting possible mechanisms for antimicrobial activity. The ZSB system was plasma deposited under various pulse conditions onto non-woven fabric, and the antimicrobial efficacy of the resultant film measured for Staphylococcus aureus and Pseudomonas aeruginosa. These results suggest the potential utility of this compound as an effective antimicrobial thin film, and confirm the critical role the ligands play in effecting antimicrobial activity.

引用

页码：1477 / 1484

页数：8

共 34 条

[1] Triclosan, a commonly used bactericide found in human milk and in the aquatic environment in Sweden [J].