Is there any role for the hydroxychloroquine (HCQ) in refractory obstetrical antiphospholipid syndrome (APS) treatment?

被引：34

作者：

De Carolis, S. ^{[1
]}

Botta, A. ^{[1
]}

Salvi, S. ^{[1
]}

di Pasquo, E. ^{[1
]}

Del Sordo, G. ^{[1
]}

Garufi, C. ^{[1
]}

Lanzone, A. ^{[1
]}

De Carolis, M. P. ^{[2
]}

机构：

[1] Univ Cattolica Sacro Cuore, Dept Obstet & Gynecol, Rome, Italy

[2] Univ Cattolica Sacro Cuore, Dept Neonatol, Rome, Italy

来源：

AUTOIMMUNITY REVIEWS | 2015年 / 14卷 / 09期

关键词：

LUPUS ANTICOAGULANT; RISK-FACTORS; ANTIBODY;

D O I：

10.1016/j.autrev.2015.04.010

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The best therapy regimen for refractory obstetrical antiphospholipid syndrome remains to be determined. Additional treatments with steroids, plasma exchanges and immunoglobulins failed to show any beneficial effect. We present a case of a woman who had a better pregnancy outcome after the administration of hydroxychloroquine (HCQ) as additional treatment. Furthermore, we highlighted that HCQ was able to dramatically reduce the antiphospholipid antibodies levels. (C) 2015 Elsevier B.V. All rights reserved.

引用

页码：760 / 762

页数：3

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