Safety of Monoclonal Antibodies in Children Affected by SARS-CoV-2 Infection

被引:13
|
作者
Romani, Lorenza [1 ]
Carducci, Francesca Ippolita Calo [1 ]
Chiurchiu, Sara [1 ]
Cursi, Laura [1 ]
De Luca, Maia [1 ]
Di Giuseppe, Martina [1 ]
Krzysztofiak, Andrzej [1 ]
Lancella, Laura [1 ]
Palma, Paolo [2 ,3 ]
Vallesi, Leonardo [4 ]
Corsetti, Tiziana [4 ]
Campana, Andrea [5 ]
Nicastri, Emanuele [6 ]
Rossi, Paolo [3 ,7 ]
Bernardi, Stefania [1 ]
机构
[1] Bambino Gesu Pediat Hosp, Immunol & Infect Dis Unit, IRCCS, I-00165 Rome, Italy
[2] Bambino Gesu Pediat Hosp, Res Unit Congenital & Perinatal Infect, IRCCS, I-00165 Rome, Italy
[3] Univ Roma Tor Vergata, Dept Syst Med, Chair Pediat, I-00133 Rome, Italy
[4] Bambino Gesu Pediat Hosp, Hosp Pharm Unit, IRCCS, I-00165 Rome, Italy
[5] Bambino Gesu Pediat Hosp, Dept Pediat, IRCCS, I-00165 Rome, Italy
[6] IRCCS, Natl Inst Infect Dis, I-00149 Rome, Italy
[7] Bambino Gesu Pediat Hosp, Acad Dept Pediat, IRCCS, I-00165 Rome, Italy
来源
CHILDREN-BASEL | 2022年 / 9卷 / 03期
关键词
COVID-19; monoclonal antibody; children;
D O I
10.3390/children9030369
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Monoclonal antibody therapies for COVID-19 have been frequently used in adults, whereas there are little data regarding the safety or efficacy of monoclonal antibody treatments in pediatric patients affected by COVID-19. We report our experience in the administration of mAb as a treatment for SARS-CoV-2 infection in children aged from 24 days to 18 years old.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] SARS-CoV-2 infection in children and adolescents: a Brazilian experience
    dos Santos, Adriana de Oliveira Ribeiro
    Lucarevschi, Bianca Rezende
    Bajerl, Mariana Hool
    Pires, Luara de Oliveira
    Ubriaco, Dafny Cristina
    Nascimento, Luiz Fernando Costa
    REVISTA PAULISTA DE PEDIATRIA, 2022, 40
  • [22] Epidemiology of SARS-CoV-2 infection and SARS-CoV-2 positive hospital admissions among children in South Africa
    Kufa, Tendesayi
    Jassat, Waasila
    Cohen, Cheryl
    Tempia, Stefano
    Masha, Maureen
    Wolter, Nicole
    Walaza, Sibongile
    Gottburg, Anne
    Govender, Nelesh P.
    Hunt, Gillian
    Shonhiwa, Andronica Moipone
    Ebonwu, Joy
    Ntshoe, Genevie
    Maruma, Wellington
    Bapela, Poncho
    Ndhlovu, Nomathamsanqa
    Mathema, Hlengani
    Modise, Motshabi
    Shuping, Liliwe
    Manana, Pinky N.
    Moore, David
    Dangor, Ziyaad
    Verwey, Charl
    Madhi, Shabir A.
    Saloojee, Haroon
    Zar, Heather J.
    Blumberg, Lucille
    INFLUENZA AND OTHER RESPIRATORY VIRUSES, 2022, 16 (01) : 34 - 47
  • [23] Clinical and laboratory characteristics of children with SARS-CoV-2 infection
    Berksoy, Emel
    Kanik, Ali
    Cicek, Alper
    Bardak, Sefika
    Elibol, Pelin
    Demir, Gulsah
    Yilmaz, Nisel
    Nalbant, Tugce
    Gokalp, Gamze
    Yilmaz Ciftdogan, Dilek
    PEDIATRIC PULMONOLOGY, 2021, 56 (12) : 3674 - 3681
  • [24] SARS-CoV-2 infection in children with chronic kidney disease
    Krishnasamy, Sudarsan
    Mantan, Mukta
    Mishra, Kirtisudha
    Kapoor, Kanika
    Brijwal, Megha
    Kumar, Manish
    Sharma, Shobha
    Swarnim, Swarnim
    Gaind, Rajni
    Khandelwal, Priyanka
    Hari, Pankaj
    Sinha, Aditi
    Bagga, Arvind
    PEDIATRIC NEPHROLOGY, 2022, 37 (04) : 849 - 857
  • [25] Characteristics of children with confirmed SARS-CoV-2 infection in Indonesia
    Soebandrio, Amin
    Kusumaningrum, Tina
    Yudhaputri, Frilasita A.
    Oktavianthi, Sukma
    Malik, Safarina G.
    Myint, Khin Saw Aye
    JOURNAL OF CLINICAL VIROLOGY PLUS, 2021, 1 (03):
  • [26] SARS-CoV-2 infection in children with chronic kidney disease
    Sudarsan Krishnasamy
    Mukta Mantan
    Kirtisudha Mishra
    Kanika Kapoor
    Megha Brijwal
    Manish Kumar
    Shobha Sharma
    Swarnim Swarnim
    Rajni Gaind
    Priyanka Khandelwal
    Pankaj Hari
    Aditi Sinha
    Arvind Bagga
    Pediatric Nephrology, 2022, 37 : 849 - 857
  • [27] Immune responses to SARS-CoV-2 infection and vaccination in children
    Brodin, Petter
    SEMINARS IN IMMUNOLOGY, 2023, 69
  • [28] SARS-CoV-2 Infection and COVID-19 in Children
    Waghmare, Alpana
    Hijano, Diego R.
    RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2025, 51 (01) : 139 - 156
  • [29] Monoclonal antibody therapies in the management of SARS-CoV-2 infection
    Miguez-Rey, Enrique
    Choi, Dasom
    Kim, Seungmin
    Yoon, Sangwook
    Sandulescu, Oana
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2022, 31 (01) : 41 - 58
  • [30] SARS-CoV-2 infection is not associated with the emergence of monoclonal gammopathies
    Simonini, Cecilia
    Natali, Patrizia
    Pirotti, Tommaso
    Nasillo, Vincenzo
    Riva, Giovanni
    Chester, Johanna
    Trenti, Tommaso
    Debbia, Daria
    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2024, 46 (03) : 451 - 456