Pilot-scale extraction and antimicrobial activity of crude extract from ovine neutrophils

被引：14

作者：

Anderson, Rachel C. ^{[1
]}

Yu, Pak-Lam ^{[1
]}

机构：

[1] Massey Univ, Biotechnol Grp, Sch Engn & Adv Technol, Palmerston North, New Zealand

来源：

PROCESS BIOCHEMISTRY | 2008年 / 43卷 / 08期

关键词：

antimicrobial peptides; cathelicidins; neutrophils; blood products;

D O I：

10.1016/j.procbio.2008.04.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Antimicrobial peptides have potential to be a high-value product purified from waste ovine blood. Previous work characterised antimicrobial peptides isolated from ovine neutrophils and determined the mechanisms of action. Here it is shown that the crude antimicrobial extract can be produced on a pilot-scale while retaining the antimicrobial activity. This crude extract could be used as a biopreservative for chilled lamb meat products or in a topical cream for treating cuts and grazes. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：882 / 886

页数：5

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