Control of host dimerization and flavin recognition via intramolecular receptor self-assembly

被引:0
|
作者
Jeoung, F
de Cremiers, HA
Deans, R
Cooke, G
Heath, SL
Vanderstraeten, PE
Rotello, VM [1 ]
机构
[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA
[2] Heriot Watt Univ, Dept Chem, Ctr Biomimet Design & Synth, Edinburgh EH14 4AS, Midlothian, Scotland
[3] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England
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中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We have synthesized a family of receptors for flavins based on 6-aryl-2,4-acyldiamino-s-triazines. In these synthetic hosts, systematic variation of the position and functionalization of a hydrogen bond-donating amide moiety on the 6-aryl ring modulates dimerization over a 17-fold range, and flavin recognition over a 7-fold range. (C) 2001 Elsevier Science Ltd. All rights reserved.
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页码:7357 / 7359
页数:3
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