Current Standards of Care and Long Term Outcomes for Thalassemia and Sickle Cell Disease

被引：23

作者：

Chonat, Satheesh ^{[1
,2
]}

Quinn, Charles T. ^{[3
]}

机构：

[1] Emory Univ, Sch Med & Ilac Canc, 2015 Uppergate Dr, Atlanta, GA 30322 USA

[2] Childrens Healthcare Atlanta, Blood Disorders Ctr, 2015 Uppergate Dr, Atlanta, GA 30322 USA

[3] Cincinnati Childrens Hosp Med Ctr, Hematol, 3333 Burnet Ave, Cincinnati, OH 45220 USA

来源：

GENE AND CELL THERAPIES FOR BETA-GLOBINOPATHIES | 2017年 / 1013卷

关键词：

Sickle cell disease; Thalassemia; Thalassaemia; Clinical care; Standard care; Outcome; FETAL-HEMOGLOBIN INDUCTION; SILENT CEREBRAL INFARCTION; LIVER IRON CONCENTRATION; BETA-THALASSEMIA; PENICILLIN PROPHYLAXIS; PULMONARY-HYPERTENSION; CONTROLLED-TRIAL; SERUM FERRITIN; YOUNG-CHILDREN; RISK-FACTORS;

D O I：

10.1007/978-1-4939-7299-9_3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Thalassemia and sickle cell disease (SCD) are disorders of hemoglobin that affect millions of people worldwide. The carrier states for these diseases arose as common, balanced polymorphisms during human history because they afforded protection against severe forms of malaria. These complex, multisystem diseases are reviewed here with a focus on current standards of clinical management and recent research findings. The importance of a comprehensive, multidisciplinary and lifelong system of care is also emphasized.

引用

页码：59 / 87

页数：29

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