Evolution: Tinkering within Gene Regulatory Landscapes

被引:13
作者
Kratochwil, Claudius F. [1 ,2 ]
Meyer, Axel [1 ]
机构
[1] Univ Konstanz, Dept Biol, Constance, Germany
[2] Univ Konstanz, Zukunftskolleg, Constance, Germany
关键词
TRANSCRIPTION FACTOR-BINDING;
D O I
10.1016/j.cub.2015.02.051
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recently evolved enhancers dominate mammalian gene regulatory landscapes. Mostly exapted from ancestral DNA sequences, many are linked to genes under positive selection. Just as RNA-seq some years ago, unbiased enhancer mapping is on the verge of changing evolutionary research.
引用
收藏
页码:R285 / R288
页数:5
相关论文
共 20 条
[1]   The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches [J].
Abzhanov, Arhat ;
Kuo, Winston P. ;
Hartmann, Christine ;
Grant, B. Rosemary ;
Grant, Peter R. ;
Tabin, Clifford J. .
NATURE, 2006, 442 (7102) :563-567
[2]  
[Anonymous], MOL ECOL RE IN PRESS
[3]   Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers [J].
Attanasio, Catia ;
Nord, Alex S. ;
Zhu, Yiwen ;
Blow, Matthew J. ;
Li, Zirong ;
Liberton, Denise K. ;
Morrison, Harris ;
Plajzer-Frick, Ingrid ;
Holt, Amy ;
Hosseini, Roya ;
Phouanenavong, Sengthavy ;
Akiyama, Jennifer A. ;
Shoukry, Malak ;
Afzal, Veena ;
Rubin, Edward M. ;
FitzPatrick, David R. ;
Ren, Bing ;
Hallgrimsson, Benedikt ;
Pennacchio, Len A. ;
Visel, Axel .
SCIENCE, 2013, 342 (6157)
[4]   The evolution of gene expression levels in mammalian organs [J].
Brawand, David ;
Soumillon, Magali ;
Necsulea, Anamaria ;
Julien, Philippe ;
Csardi, Gabor ;
Harrigan, Patrick ;
Weier, Manuela ;
Liechti, Angelica ;
Aximu-Petri, Ayinuer ;
Kircher, Martin ;
Albert, Frank W. ;
Zeller, Ulrich ;
Khaitovich, Philipp ;
Gruetzner, Frank ;
Bergmann, Sven ;
Nielsen, Rasmus ;
Paeaebo, Svante ;
Kaessmann, Henrik .
NATURE, 2011, 478 (7369) :343-+
[5]   Evolution at two levels: On genes and form [J].
Carroll, SB .
PLOS BIOLOGY, 2005, 3 (07) :1159-1166
[6]   Jacob and Monod: From Operons to EvoDevo [J].
Gann, Alexander .
CURRENT BIOLOGY, 2010, 20 (17) :R718-R723
[7]   A molecular basis for classic blond hair color in Europeans [J].
Guenther, Catherine A. ;
Tasic, Bosiljka ;
Luo, Liqun ;
Bedell, Mary A. ;
Kingsley, David M. .
NATURE GENETICS, 2014, 46 (07) :748-752
[8]   The locus of evolution: Evo devo and the genetics of adaptation [J].
Hoekstra, Hopi E. ;
Coyne, Jerry A. .
EVOLUTION, 2007, 61 (05) :995-1016
[9]   EVOLUTION AND TINKERING [J].
JACOB, F .
SCIENCE, 1977, 196 (4295) :1161-1166
[10]   EVOLUTION AT 2 LEVELS IN HUMANS AND CHIMPANZEES [J].
KING, MC ;
WILSON, AC .
SCIENCE, 1975, 188 (4184) :107-116