A new pyrene-based fluorescent probe with large Stokes shift for detecting hydrogen peroxide in aqueous solution and living cells

被引：24

作者：

Nie, Jing ^{[1
,2
]}

Liu, Yong ^{[2
]}

Niu, Jie ^{[2
]}

Ni, Zhonghai ^{[1
]}

Lin, Weiying ^{[2
]}

机构：

[1] China Univ Min & Technol, Sch Chem Engn & Technol, Xuzhou 221116, Jiangsu, Peoples R China

[2] Univ Jinan, Sch Chem & Chem Engn, Sch Mat Sci & Engn, Inst Fluorescent Probes Biol Imaging, Jinan 250022, Shandong, Peoples R China

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 2017年 / 348卷

关键词：

Fluorescent probe; Stokes shift; Hydrogen peroxide; GLUCOSE; BIOLOGY; STRESS; CANCER; WATER; H2O2;

D O I：

10.1016/j.jphotochem.2017.08.008

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Hydrogen peroxide (H2O2) plays an important role in signal transduction and therapy of serious diseases. In this work, we have developed a new pyrene-based fluorescent probe Py-Boe, which possesses large Stokes shift and achieves detection of H2O2 in aqueous solution. The probe Py-Boe exhibits excellent photostability, high sensitive and selectivity. Taking advantage of these properties, the probe Py-Boe achieves succussfully imaging of exogenous and endogenous H2O2 in living RAW 264.7 cells. We expect that this dye with large Stokes shift may open an avenue to construct novel fluorescent probe with large Stokes shift for biological application. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：1 / 7

页数：7

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